Department of Neurology Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán México City México.
Brain Behav. 2016 May 17;6(7):e00466. doi: 10.1002/brb3.466. eCollection 2016 Jul.
Quantitative Sensory Testing (QST) is more often used because of the increasing recognition of small fiber neuropathy.
We studied QST in a systematic way in an age-stratified cohort of 83 neurological-free Hispanic Latinamerican patients. Predefined standardized stimuli were applied using the method of limits.
WDT range from 2.2 to 3.3°C in hands, and from 4.0°C up to 6.6°C in feet. Cold detection threshold range from 2.2 to 3.6°C in hands, and from 2.6°C to 4.5°C in feet. Heat-induced pain (HP) was induced at lower temperatures than previously reported, with a range from 41.8°C to 44.5°C in hands and from 43.2 to 45.7°C in feet. Similar to HP, cold pain was also induced at much higher temperatures, between 21.4-17.3°C in hands and 21.5-16.5°C in feet. Vibratory stimuli ranged from 0.8 to 1.7 μ/sec in hands and from 1.4 to 3.5 μ/sec in feet.
Temperature and vibration thresholds were similar to those previously reported in other populations except for pain thresholds that were lower in this population than in the Caucasian population.
由于对小纤维神经病认识的提高,定量感觉测试(QST)应用得越来越多。
我们对 83 名无神经科疾病的拉丁裔西班牙裔患者进行了分层年龄队列的系统 QST 研究。使用极限法施加了预定义的标准化刺激。
手部的 WDT 范围为 2.2 至 3.3°C,足部为 4.0°C 至 6.6°C。手部的冷觉检测阈值范围为 2.2 至 3.6°C,足部为 2.6°C 至 4.5°C。与之前报道的相比,热诱导疼痛(HP)的诱导温度更低,手部的范围为 41.8°C 至 44.5°C,足部为 43.2°C 至 45.7°C。与 HP 相似,冷痛也在更高的温度下诱发,手部为 21.4-17.3°C,足部为 21.5-16.5°C。振动刺激在手部的范围为 0.8 至 1.7 μ/sec,在足部为 1.4 至 3.5 μ/sec。
除了疼痛阈值低于白种人之外,温度和振动阈值与其他人群的先前报道相似。