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腰椎原发性神经内分泌肿瘤:酷似脊柱神经鞘瘤的罕见肿瘤。

Primary Neuroendocrine Tumor of the Lumbar Spine: Rare Tumor Mimicking Nerve Sheath Tumor of the Spine.

作者信息

Kumar Sanjay, Maheshwari Vikas, Mukherjee Aishik, Raman Deep Kumar

机构信息

Department of Neurosurgery, Command Hospital (Southern Command), Pune, Maharashtra, India.

Department of Pathology, Armed Forces Medical College, Pune, Maharashtra, India.

出版信息

Asian J Neurosurg. 2019 Jul-Sep;14(3):894-896. doi: 10.4103/ajns.AJNS_276_18.

Abstract

Neuroendocrine tumors (Carcinoid tumors) generally arise from enterochromaffin cells of gut and bronchi. Primary carcinoid tumors of spine are extremely rare and have been described in sacrum and coccyx. Primary carcinoid tumors involving the spinal cord are still rarer, and review of literature revealed only two cases reported. Our patient a 39-year-old male had diagnosed as a case of nerve sheath tumor (intradural extramedullary) at LV4 region on neuroimaging. However, postoperatively, the tumor turned out to be a rare primary spinal carcinoid tumor on histopathological examination and immunohistochemical staining. Work up to rule out any other site in the body was negative. To the best of our knowledge, this is the first case of primary carcinoid tumor of the lumbar spine.

摘要

神经内分泌肿瘤(类癌肿瘤)通常起源于肠道和支气管的肠嗜铬细胞。脊柱原发性类癌肿瘤极为罕见,已有骶骨和尾骨的相关报道。累及脊髓的原发性类癌肿瘤更为罕见,文献复习仅发现两例报道。我们的患者是一名39岁男性,神经影像学检查诊断为L4区域的神经鞘瘤(硬脊膜内髓外)。然而,术后经组织病理学检查和免疫组化染色,肿瘤竟是罕见的原发性脊柱类癌肿瘤。排除身体其他部位病变的检查结果为阴性。据我们所知,这是首例腰椎原发性类癌肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c4f/6702991/228a0684dc93/AJNS-14-894-g001.jpg

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