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脊髓髓内原发性类癌肿瘤:病例报告及文献复习。

Primary carcinoid tumor of medulla spinalis: case report and review of the literature.

机构信息

Department of Neurosurgery of the First Clinical Hospital, Jilin University, 71 Xinmin St, Changchun 130021, China.

出版信息

Eur J Med Res. 2014 Dec 19;19(1):71. doi: 10.1186/s40001-014-0071-7.

Abstract

BACKGROUND

Carcinoid tumors are slow growing neuroendocrine tumors which can originate from various sites within the body. A carcinoid tumor originating in the medulla spinalis has not previously been reported in the literature.

CASE REPORT

We report a case of a 33-year-old man, presenting with a five-month history of bilateral lower extremity pain, as well as paresthesia, and mild weakness in one lateral lower extremity. A lumbar laminectomy of L3 to L5 and en bloc resection of the tumor was performed. Postoperative histopathology and immunohistochemical analysis of the tumor were consistent with that of a carcinoid tumor. There were no clinical or radiological signs of tumor recurrence or metastasis at the patient's two year postoperative follow-up.

CONCLUSIONS

During the differential diagnosis of medulla spinalis tumors, the possibility of a primary carcinoid tumor originating within the medulla spinalis should be considered. An accurate tumor classification is imperative to ensure that the most effective course of treatment is pursued.

摘要

背景

类癌肿瘤是生长缓慢的神经内分泌肿瘤,可起源于体内的各种部位。起源于脊髓髓质的类癌肿瘤以前在文献中尚未报道。

病例报告

我们报告了一例 33 岁男性,表现为双侧下肢疼痛五个月,以及单侧下肢感觉异常和轻度无力。进行了 L3 至 L5 的腰椎椎板切除术和肿瘤整块切除术。肿瘤的术后组织病理学和免疫组织化学分析与类癌肿瘤一致。在患者术后两年的随访中,没有临床或影像学迹象表明肿瘤复发或转移。

结论

在脊髓肿瘤的鉴别诊断中,应考虑源自脊髓髓质的原发性类癌肿瘤的可能性。准确的肿瘤分类对于确保采用最有效的治疗方法至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca35/4272791/0e7e26e97c0f/40001_2014_71_Fig1_HTML.jpg

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