Department of Neurosurgery of the First Clinical Hospital, Jilin University, 71 Xinmin St, Changchun 130021, China.
Eur J Med Res. 2014 Dec 19;19(1):71. doi: 10.1186/s40001-014-0071-7.
Carcinoid tumors are slow growing neuroendocrine tumors which can originate from various sites within the body. A carcinoid tumor originating in the medulla spinalis has not previously been reported in the literature.
We report a case of a 33-year-old man, presenting with a five-month history of bilateral lower extremity pain, as well as paresthesia, and mild weakness in one lateral lower extremity. A lumbar laminectomy of L3 to L5 and en bloc resection of the tumor was performed. Postoperative histopathology and immunohistochemical analysis of the tumor were consistent with that of a carcinoid tumor. There were no clinical or radiological signs of tumor recurrence or metastasis at the patient's two year postoperative follow-up.
During the differential diagnosis of medulla spinalis tumors, the possibility of a primary carcinoid tumor originating within the medulla spinalis should be considered. An accurate tumor classification is imperative to ensure that the most effective course of treatment is pursued.
类癌肿瘤是生长缓慢的神经内分泌肿瘤，可起源于体内的各种部位。起源于脊髓髓质的类癌肿瘤以前在文献中尚未报道。
我们报告了一例 33 岁男性，表现为双侧下肢疼痛五个月，以及单侧下肢感觉异常和轻度无力。进行了 L3 至 L5 的腰椎椎板切除术和肿瘤整块切除术。肿瘤的术后组织病理学和免疫组织化学分析与类癌肿瘤一致。在患者术后两年的随访中，没有临床或影像学迹象表明肿瘤复发或转移。
在脊髓肿瘤的鉴别诊断中，应考虑源自脊髓髓质的原发性类癌肿瘤的可能性。准确的肿瘤分类对于确保采用最有效的治疗方法至关重要。
