• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

中枢神经系统原发性类癌肿瘤:一例诊断具有挑战性的罕见病例报告

Primary Carcinoid Tumor of the Central Nervous System: A Rare Case Report with a Diagnostic Challenge.

作者信息

Singh Anurag, Singh Alka, Bhaisora Kamlesh Singh, Krishnani Narendra

机构信息

Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India.

Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India.

出版信息

Int J Appl Basic Med Res. 2025 Apr-Jun;15(2):128-131. doi: 10.4103/ijabmr.ijabmr_523_24. Epub 2025 Apr 7.

DOI:10.4103/ijabmr.ijabmr_523_24
PMID:40343248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12058044/
Abstract

Carcinoid tumors (CTs) are slow-growing neuroendocrine neoplasms that may arise in any part of the body. They usually affect the lungs or gut. Primary intradural extramedullary CTs of the central nervous system are rare; few cases have been reported. This case report describes a 36-year-old patient with lower back discomfort, weakness, and lower leg pain for 8 months. Contrast-enhanced magnetic resonance imaging of the lumbosacral spine, from the lower L3 vertebral level to the L4-5 disc level, revealed a 4.5 cm × 2.5 cm × 1.5 cm intradural mass lesion. The main differential diagnoses were on clinical and radiographic examination: nerve sheath tumors, meningiomas, and myxopapillary ependymomas. The tumor was excised en bloc after an L3-L5 lumbar laminectomy. Histomorphology and immunohistochemistry made a definitive diagnosis of CT of the lumbar spine. Two years after surgery, there was no clinical or radiological evidence of tumor recurrence or metastasis. The present case study is intended to effectively diagnose and treat spinal intradural extramedullary CTs.

摘要

类癌肿瘤(CTs)是生长缓慢的神经内分泌肿瘤,可发生于身体的任何部位。它们通常影响肺部或肠道。中枢神经系统原发性硬脊膜内髓外类癌肿瘤罕见,仅有少数病例报道。本病例报告描述了一名36岁患者,其下背部不适、无力及小腿疼痛8个月。腰骶部脊柱的增强磁共振成像显示,从L3椎体下部至L4 - 5椎间盘水平有一个4.5 cm×2.5 cm×1.5 cm的硬脊膜内肿块病变。临床和影像学检查的主要鉴别诊断包括:神经鞘瘤、脑膜瘤和黏液乳头型室管膜瘤。在L3 - L5腰椎椎板切除术后,肿瘤被整块切除。组织形态学和免疫组化确诊为腰椎类癌肿瘤。术后两年,无肿瘤复发或转移的临床及影像学证据。本病例研究旨在有效诊断和治疗脊柱硬脊膜内髓外类癌肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e52/12058044/9807448696d1/IJABMR-15-128-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e52/12058044/664c8a4c43d6/IJABMR-15-128-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e52/12058044/9807448696d1/IJABMR-15-128-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e52/12058044/664c8a4c43d6/IJABMR-15-128-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e52/12058044/9807448696d1/IJABMR-15-128-g002.jpg

相似文献

1
Primary Carcinoid Tumor of the Central Nervous System: A Rare Case Report with a Diagnostic Challenge.中枢神经系统原发性类癌肿瘤:一例诊断具有挑战性的罕见病例报告
Int J Appl Basic Med Res. 2025 Apr-Jun;15(2):128-131. doi: 10.4103/ijabmr.ijabmr_523_24. Epub 2025 Apr 7.
2
Incidental Primary Intradural Carcinoid Tumor in a Patient with Lumbar Radiculopathy.一名患有腰椎神经根病患者的偶然发现的原发性硬脊膜内类癌肿瘤。
World Neurosurg. 2017 Sep;105:1042.e11-1042.e14. doi: 10.1016/j.wneu.2017.06.179. Epub 2017 Jul 11.
3
Giant Invasive Intradural Extramedullary Lumbar Schwannoma: A Case Report and Literature Review.巨大侵袭性硬脊膜内髓外腰椎神经鞘瘤:病例报告及文献综述
Cureus. 2023 Jun 20;15(6):e40708. doi: 10.7759/cureus.40708. eCollection 2023 Jun.
4
Intradural disc herniation at L5 level mimicking an intradural spinal tumor.L5 水平硬脊膜内椎间盘突出,类似硬脊膜内脊髓肿瘤。
Eur Spine J. 2011 Jul;20 Suppl 2(Suppl 2):S326-9. doi: 10.1007/s00586-011-1772-z. Epub 2011 Mar 23.
5
Intradural hemangiopericytoma of the lumbar spine: case report.腰椎硬膜内血管外皮细胞瘤:病例报告
Neurosurgery. 2002 Mar;50(3):654-7. doi: 10.1097/00006123-200203000-00045.
6
Primary Neuroendocrine Tumor of the Lumbar Spine: Rare Tumor Mimicking Nerve Sheath Tumor of the Spine.腰椎原发性神经内分泌肿瘤:酷似脊柱神经鞘瘤的罕见肿瘤。
Asian J Neurosurg. 2019 Jul-Sep;14(3):894-896. doi: 10.4103/ajns.AJNS_276_18.
7
Intradural Carcinoid Tumor Found in a Patient with No History of Cancer.在一名无癌症病史的患者中发现硬脊膜内类癌肿瘤。
World Neurosurg. 2016 Dec;96:607.e1-607.e6. doi: 10.1016/j.wneu.2016.09.088. Epub 2016 Oct 3.
8
Intradural disc herniation at L5-S1 mimicking an intradural extramedullary spinal tumor: a case report.L5-S1节段硬膜内椎间盘突出症误诊为硬膜内髓外脊髓肿瘤:一例报告
J Korean Med Sci. 2006 Aug;21(4):778-80. doi: 10.3346/jkms.2006.21.4.778.
9
Inflammatory myofibroblastic tumor in the intradural extramedullary space of the lumbosacral spine: a case report and review of the literature.腰骶椎管内硬脊膜外炎性肌纤维母细胞瘤:病例报告及文献复习。
Childs Nerv Syst. 2024 Nov 30;41(1):24. doi: 10.1007/s00381-024-06690-4.
10
Utility of Multimodal Intraoperative Neuromonitoring for Excision of Filum Terminale Ependymoma in Close Proximity to Conus.多模态术中神经监测在靠近终丝圆锥的情况下切除终丝室管膜瘤的效用。
World Neurosurg. 2024 Sep;189:53-54. doi: 10.1016/j.wneu.2024.05.111. Epub 2024 May 23.

本文引用的文献

1
Myxopapillary Ependymoma-a Case Report of Rare Multicentric Subtype and Literature Review.黏液性乳头状室管膜瘤——一种罕见的多中心亚型病例报告及文献复习。
Med Arch. 2023 Apr;77(2):150-154. doi: 10.5455/medarh.2023.77.150-154.
2
Neuroendocrine neoplasms of the lung and gastrointestinal system: convergent biology and a path to better therapies.肺和胃肠系统神经内分泌肿瘤:趋同生物学和改善治疗方法的途径。
Nat Rev Clin Oncol. 2023 Jan;20(1):16-32. doi: 10.1038/s41571-022-00696-0. Epub 2022 Oct 28.
3
Classification of neuroendocrine neoplasms: lights and shadows.
神经内分泌肿瘤的分类:光明与阴影。
Rev Endocr Metab Disord. 2021 Sep;22(3):527-538. doi: 10.1007/s11154-020-09612-2. Epub 2020 Nov 9.
4
Gastric neuroendocrine tumor: A practical literature review.胃神经内分泌肿瘤:实用文献综述
World J Gastrointest Oncol. 2020 Aug 15;12(8):850-856. doi: 10.4251/wjgo.v12.i8.850.
5
Primary Neuroendocrine Tumor of the Lumbar Spine: Rare Tumor Mimicking Nerve Sheath Tumor of the Spine.腰椎原发性神经内分泌肿瘤:酷似脊柱神经鞘瘤的罕见肿瘤。
Asian J Neurosurg. 2019 Jul-Sep;14(3):894-896. doi: 10.4103/ajns.AJNS_276_18.
6
Intradural Extramedullary Spinal Neoplasms: Radiologic-Pathologic Correlation.椎管内髓外肿瘤:放射-病理相关性。
Radiographics. 2019 Mar-Apr;39(2):468-490. doi: 10.1148/rg.2019180200.
7
Incidental Primary Intradural Carcinoid Tumor in a Patient with Lumbar Radiculopathy.一名患有腰椎神经根病患者的偶然发现的原发性硬脊膜内类癌肿瘤。
World Neurosurg. 2017 Sep;105:1042.e11-1042.e14. doi: 10.1016/j.wneu.2017.06.179. Epub 2017 Jul 11.
8
Intradural Carcinoid Tumor Found in a Patient with No History of Cancer.在一名无癌症病史的患者中发现硬脊膜内类癌肿瘤。
World Neurosurg. 2016 Dec;96:607.e1-607.e6. doi: 10.1016/j.wneu.2016.09.088. Epub 2016 Oct 3.
9
Primary carcinoid tumor of medulla spinalis: case report and review of the literature.脊髓髓内原发性类癌肿瘤:病例报告及文献复习。
Eur J Med Res. 2014 Dec 19;19(1):71. doi: 10.1186/s40001-014-0071-7.
10
Spinal carcinoid metastasis: rare but important differential diagnosis of a spinal mass.脊髓类癌转移:一种罕见但重要的脊髓肿块鉴别诊断。
World Neurosurg. 2011 Nov;76(5):415-6. doi: 10.1016/j.wneu.2010.11.023.