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氢氯噻嗪与文拉法辛:药物性大疱性类天疱疮

Hydrochlorothiazide vs Venlafaxine: Drug-induced Bullous Pemphigoid.

作者信息

Naramala Srikanth, Dalal Hussain, Adapa Sreedhar, Patel Pallav, Konala Venu Madhav

机构信息

Rheumatology, Adventist Medical Center, Hanford, USA.

Internal Medicine, Internal Medicine Multi-Specialty Clinic, Houston, USA.

出版信息

Cureus. 2019 Jun 25;11(6):e4999. doi: 10.7759/cureus.4999.

Abstract

Pemphigoid group of dermatologic conditions is a group of autoimmune skin disorders resulting in blistering skin conditions. The two diseases that fall under this category are bullous pemphigoid and pemphigus vulgaris. While there are many similarities in these two disorders, there are numerous pathologic and biochemical differences which help us differentiate between these disorders. In this case report, we report a usual manifestation of bullous pemphigoid in a 72-year-old female secondary to use of a well-known antihypertensive (hydrochlorothiazide) and/or venlafaxine (anti-depressant).

摘要

天疱疮类皮肤病是一组自身免疫性皮肤病,可导致皮肤出现水疱。属于这一类别的两种疾病是大疱性类天疱疮和寻常型天疱疮。虽然这两种疾病有许多相似之处,但也存在许多病理和生化差异,有助于我们区分这些疾病。在本病例报告中,我们报告了一名72岁女性因使用一种知名降压药(氢氯噻嗪)和/或文拉法辛(抗抑郁药)继发大疱性类天疱疮的常见表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85b9/6713256/e00c7a4033d8/cureus-0011-00000004999-i01.jpg

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