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伪装成成人发作性特应性皮炎的大疱性类天疱疮病例。

Case of Bullous Pemphigoid Masquerading as Adult-Onset Atopic Dermatitis.

作者信息

Nojima Mai, Ticknor Iesha L, Sazegar Payam

机构信息

Kaiser Permanente Bernard J Tyson School of Medicine, Pasadena, CA, USA.

Kaiser Permanente San Diego Medical Center, San Diego, CA, USA.

出版信息

Perm J. 2024 Sep 16;28(3):177-179. doi: 10.7812/TPP/24.043. Epub 2024 Aug 9.

DOI:10.7812/TPP/24.043
PMID:39118435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11404639/
Abstract

The majority of dermatitis cases in adults result from chronic or relapsing atopic dermatitis in childhood. Adult-onset atopic dermatitis, also known as idiopathic chronic eczematous eruption of aging (CEEA), is a phenomenon seen in adults 50 years and older with no prior history of atopic dermatitis. CEEA is often a diagnosis of exclusion after ruling out more serious causes of dermatitis including bullous pemphigoid (BP), allergic conditions, and hematologic malignancies. This report details the case of a 67-year-old woman with no history of atopy who presented with a persistent, eczematous dermatitis not responsive to traditional therapy, consistent with CEEA, but was later identified as BP.

摘要

大多数成人的皮炎病例源于儿童时期的慢性或复发性特应性皮炎。成人发病的特应性皮炎,也称为老年性特发性慢性湿疹样皮疹(CEEA),是一种在50岁及以上且无特应性皮炎既往史的成年人中出现的现象。CEEA通常是在排除了包括大疱性类天疱疮(BP)、过敏性疾病和血液系统恶性肿瘤等更严重的皮炎病因后作出的排除性诊断。本报告详细介绍了一名67岁无特应性病史的女性病例,该患者出现持续性湿疹性皮炎,对传统治疗无反应,符合CEEA,但后来被确诊为BP。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e1/11404639/bf00c04eeaf1/tpp_24.043-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e1/11404639/bf00c04eeaf1/tpp_24.043-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e1/11404639/bf00c04eeaf1/tpp_24.043-g001.jpg

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本文引用的文献

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Treatment Strategies for Chronic Pruritus and Eczema/Dermatitis in Older Adults Under the Category of Chronic Eczematous Eruptions of Aging (CEEA).老年人慢性瘙痒症和湿疹/皮炎的治疗策略属于老年慢性湿疹性发作(CEEA)类别。
Am J Clin Dermatol. 2023 May;24(3):405-418. doi: 10.1007/s40257-023-00767-7. Epub 2023 Mar 15.
2
Pemphigus Vulgaris and Bullous Pemphigoid: Update on Diagnosis and Treatment.寻常型天疱疮和大疱性类天疱疮:诊断与治疗的最新进展
Dermatol Pract Concept. 2020 Jun 29;10(3):e2020050. doi: 10.5826/dpc.1003a50. eCollection 2020 Jul.
3
Hydrochlorothiazide vs Venlafaxine: Drug-induced Bullous Pemphigoid.
氢氯噻嗪与文拉法辛:药物性大疱性类天疱疮
Cureus. 2019 Jun 25;11(6):e4999. doi: 10.7759/cureus.4999.
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Bullous pemphigoid.大疱性类天疱疮
An Bras Dermatol. 2019 Mar-Apr;94(2):133-146. doi: 10.1590/abd1806-4841.20199007. Epub 2019 May 9.
5
A Retrospective Review of New-onset Dermatitis in Patients Aged 60 Years or Older.60岁及以上患者新发皮炎的回顾性研究
J Clin Aesthet Dermatol. 2018 Jan;11(1):19-20. Epub 2018 Jan 1.
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A systematic review of the safety and efficacy of systemic corticosteroids in atopic dermatitis.系统评价全身性皮质类固醇治疗特应性皮炎的安全性和疗效。
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Atopic Dermatitis in Adults: A Diagnostic Challenge.成人特应性皮炎:一项诊断挑战。
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