School of Engineering, Indian Institute of Technology Mandi, Mandi, Himachal Pradesh, India.
Proc Inst Mech Eng H. 2021 Feb;235(2):185-196. doi: 10.1177/0954411920967775. Epub 2020 Nov 3.
Extreme bone resorption due to bone remodelling is one of the reasons for ankle component loosening. Finite element (FE) analysis has been effectively used nowadays for pre-clinical analysis of orthopaedic implants. For FE modelling, the selection of bone material and dead zone play a vital role to understand the bone remodelling. This study deals with the effects of different cancellous elastic modulus-density relationships and dead zone on bone remodelling around the tibia owing to total ankle replacement (TAR), using finite element analysis with physiological loading conditions. This study also investigated the bone stimulus distribution in the tibia to identify the initial indication of bone density changes due to bone remodelling. Additionally, the Hoffman failure criterion was used to investigate the chances of implant-bone interface failure due to different cancellous bone material modelling and bone remodelling. The present bone remodelling study consists of three different dead or lazy zones (±0.75, ±0.60 and ±0.35) to examine the influence of the dead zone on bone remodelling. Differences in stress/strain distribution were observed in the tibia bone due to different cancellous bone material modelling. Despite little variations, bone density changes due to bone remodelling were found to be almost similar for two FE models having different cancellous bone material. Similar to these results, the effect of different dead zone on bone density changes due to bone remodelling was found to be minimal. Bone stimulus distribution in the cancellous bone was found to be almost similar for FE models having different cancellous bone material modelling and different dead zones. To understand the stress/strain and interface related failure of the tibial component, cancellous bone material modelling plays a crucial role. However, cancellous bone material modelling and dead zone have minimal influence on bone remodelling around the tibia cancellous bone due to TAR.
由于骨重建导致的极端骨吸收是踝关节部件松动的原因之一。有限元（FE）分析如今已被有效地用于矫形植入物的临床前分析。对于 FE 建模，选择骨材料和死区对于理解骨重建起着至关重要的作用。本研究使用有限元分析和生理加载条件，研究了不同松质骨弹性模量-密度关系和死区对全踝关节置换（TAR）后胫骨周围骨重建的影响。本研究还研究了胫骨中的骨刺激分布，以确定由于骨重建导致的骨密度变化的初始迹象。此外，使用 Hoffman 失效准则研究了由于不同的松质骨材料建模和骨重建导致植入物-骨界面失效的可能性。本骨重建研究包括三个不同的死区或懒区（±0.75、±0.60 和 ±0.35），以检查死区对骨重建的影响。由于不同的松质骨材料建模，胫骨中的应力/应变分布存在差异。尽管存在微小差异，但由于两种具有不同松质骨材料的 FE 模型，骨密度变化由于骨重建而几乎相似。类似的结果表明，不同的死区对由于骨重建导致的骨密度变化的影响最小。具有不同的松质骨材料建模和不同的死区的 FE 模型中的松质骨中的骨刺激分布几乎相似。为了了解胫骨部件的应力/应变和界面相关失效，松质骨材料建模起着至关重要的作用。然而，由于 TAR，松质骨材料建模和死区对 TAR 后胫骨松质骨周围的骨重建的影响最小。
