Lipid Metabolism: A New Player in the Conundrum of Lung Fibrosis.
作者信息
Summer Ross, Mora Ana L
机构信息
Jane and Leonard Korman Respiratory InstituteThomas Jefferson UniversityPhiladelphia, Pennsylvaniaand.
Aging InstituteDivision of Pulmonary, Allergy and Critical Care MedicineDepartment of MedicineUniversity of PittsburghPittsburgh, Pennsylvania.
出版信息
Am J Respir Cell Mol Biol. 2019 Dec;61(6):669-670. doi: 10.1165/rcmb.2019-0098ED.
Abstract
摘要
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本文引用的文献
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Am J Respir Cell Mol Biol. 2019 Dec;61(6):737-746. doi: 10.1165/rcmb.2018-0324OC.
2
Metformin reverses established lung fibrosis in a bleomycin model.二甲双胍可逆转博莱霉素模型中已建立的肺纤维化。
Nat Med. 2018 Aug;24(8):1121-1127. doi: 10.1038/s41591-018-0087-6. Epub 2018 Jul 2.
3
Lipid Synthesis Is Required to Resolve Endoplasmic Reticulum Stress and Limit Fibrotic Responses in the Lung.脂质合成对于缓解内质网应激和限制肺部纤维化反应是必需的。
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Idiopathic Pulmonary Fibrosis: Aging, Mitochondrial Dysfunction, and Cellular Bioenergetics.特发性肺纤维化：衰老、线粒体功能障碍与细胞生物能量学
Front Med (Lausanne). 2018 Feb 5;5:10. doi: 10.3389/fmed.2018.00010. eCollection 2018.
5
Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury.肥胖诱导的脂肪因子失衡损害小鼠肺血管内皮功能，并使肺易于发生损伤。
Sci Rep. 2015 Jun 12;5:11362. doi: 10.1038/srep11362.
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Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2048-57. doi: 10.1073/pnas.1415111112. Epub 2015 Apr 6.
7
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.PINK1基因缺陷会损害线粒体稳态并促进肺纤维化。
J Clin Invest. 2015 Feb;125(2):521-38. doi: 10.1172/JCI74942. Epub 2014 Dec 22.
8
The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis.线粒体心磷脂重塑酶溶血心磷脂酰基转移酶是肺纤维化的一个新靶点。
Am J Respir Crit Care Med. 2014 Jun 1;189(11):1402-15. doi: 10.1164/rccm.201310-1917OC.
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Nat Commun. 2013;4:2563. doi: 10.1038/ncomms3563.
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