Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, Interdisciplinary Department of Medicine, University of Bari, School of Medicine, Policlinico, Bari, Italy,
Rutigliano, Bari, Italy.
Front Horm Res. 2019;53:18-32. doi: 10.1159/000494900. Epub 2019 Sep 9.
Differences between males and females are commonly attributed to sexual hormones. Androgens are responsible for the development of primary and secondary sexual characteristics in males, whereas they influence sexual behaviour, glycaemic control, lipid profile, bone metabolism and erythropoiesis in both sexes. In this chapter, we discuss preclinical and clinical data on sex-specific androgen metabolism and androgen effect on body composition.
男性和女性之间的差异通常归因于性激素。雄激素负责男性的第一性征和第二性征的发育,而它们在两性中均影响性行为、血糖控制、血脂谱、骨代谢和红细胞生成。在本章中,我们讨论了关于性别特异性雄激素代谢和雄激素对身体成分影响的临床前和临床数据。