饮食对代谢的影响存在性别差异。
Sex-Specific Variation in Metabolic Responses to Diet.
机构信息
Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY 40506, USA.
Center for Muscle Biology, College of Health Sciences, University of Kentucky, Lexington, KY 40536, USA.
出版信息
Nutrients. 2024 Sep 1;16(17):2921. doi: 10.3390/nu16172921.
Abstract
Suboptimal nutrition is a leading cause of cardiometabolic disease and mortality. Biological sex is a variable that influences individual responses to dietary components and may modulate the impact of diet on metabolic health and disease risk. This review describes findings of studies reporting how biological sex may associate with or affect metabolic outcomes or disease risk in response to varying dietary macronutrient content, Mediterranean diet, Western diet, and medical very low-calorie diet. Although few dietary interventions have been specifically designed to identify sex-diet interactions, future studies improving understanding how sex influences dietary responses could inform precision nutrition interventions for disease prevention and management.
摘要
营养状况不佳是导致心血管代谢疾病和死亡的主要原因之一。生物学性别是一个影响个体对饮食成分反应的变量，可能调节饮食对代谢健康和疾病风险的影响。本综述描述了报告生物学性别如何与代谢结果或疾病风险相关联或影响代谢结果或疾病风险的研究结果，这些研究结果是针对不同的膳食宏量营养素含量、地中海饮食、西方饮食和医学极低卡路里饮食做出的反应。尽管很少有饮食干预措施专门设计用于确定性别-饮食相互作用，但未来的研究改善对性别如何影响饮食反应的理解，可以为疾病预防和管理提供精准营养干预措施。
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