Clinic of Oncology and Department of Radiotherapy, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Cracow Branch, Garncarska 11, 31-115, Cracow, Poland.
Department of Pathology, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Cracow Branch, Garncarska 11, 31-115, Cracow, Poland.
Strahlenther Onkol. 2019 Nov;195(11):1028-1032. doi: 10.1007/s00066-019-01516-8. Epub 2019 Sep 9.
Primary lymphoepithelioma-like carcinoma of the skin (LELCS) is a very rare cutaneous neoplasm. Only about 70 cases have been documented in the literature. There are no prospective data regarding treatment methods. Surgical excision is sufficient therapy in the majority of cases. Radiation therapy is sometimes used in case of recurrence or positive margins after surgery. The metastatic potential of LELCS is extremely low and only five previously documented cases of lymph node spread have been reported. We present the case of an 80-year-old male with a tumor primarily located on the lower eyelid, with two regional recurrences and cervical lymph node spread after surgery, treated with concurrent chemoradiation. According to the available data, this is the first case of lymph node spread from an eyelid location and the first nodal recurrence after surgery.
皮肤原发性淋巴上皮样癌（LELCS）是一种非常罕见的皮肤肿瘤。文献中仅记载了约 70 例。关于治疗方法尚无前瞻性数据。在大多数情况下，手术切除是足够的治疗方法。对于术后复发或边缘阳性的情况，有时会使用放射治疗。LELCS 的转移潜能极低，仅有 5 例先前记录的淋巴结转移病例。我们报告了一例 80 岁男性病例，其肿瘤主要位于下眼睑，术后出现两处局部复发和颈部淋巴结转移，采用同期放化疗治疗。根据现有数据，这是首例来自眼睑部位的淋巴结转移病例，也是术后首例淋巴结复发病例。
