皮肤淋巴上皮瘤样癌：1例伴有神经周围侵犯的病例
Lymphoepithelioma-like Carcinoma of the Skin: A Case with Perineural Invasion.
作者信息
Lassen Cecilie B, Lock-Andersen Jørgen
机构信息
Department of Plastic Surgery, Roskilde Hospital, University of Copenhagen, Roskilde, Denmark.
出版信息
Plast Reconstr Surg Glob Open. 2014 Dec 5;2(11):e252. doi: 10.1097/GOX.0000000000000215. eCollection 2014 Nov.
Lymphoepithelioma-like carcinoma of the skin is a rare, low malignant cutaneous neoplasm. We report a case of an elderly woman with lymphoepithelioma-like carcinoma of the skin in the forehead. The tumor was mistaken first as actinic keratosis and later as metastatic squamous cell carcinoma. A histological reassessment showed lymphoepithelioma-like carcinoma of the skin with perineural invasion, which is rare and considered more aggressive. The patient therefore received adjuvant radiotherapy after the recommended wide excision. Lymphoepithelioma-like carcinoma of the skin is a variant of squamous cell carcinoma, and histologically, it resembles the more aggressive lymphoepithelioma of the nasopharynx. The later is Epstein-Barr positive, whereas lymphoepithelioma-like carcinoma normally is not. Lymphoepithelioma-like carcinoma is an important diagnosis to know and the disease is discussed.
皮肤淋巴上皮瘤样癌是一种罕见的低恶性皮肤肿瘤。我们报告一例前额皮肤淋巴上皮瘤样癌的老年女性病例。该肿瘤最初被误诊为光化性角化病，后来又被误诊为转移性鳞状细胞癌。组织学重新评估显示为伴有神经周围浸润的皮肤淋巴上皮瘤样癌，这种情况罕见且被认为更具侵袭性。因此，患者在接受推荐的广泛切除术后接受了辅助放疗。皮肤淋巴上皮瘤样癌是鳞状细胞癌的一种变体，在组织学上，它类似于侵袭性更强的鼻咽淋巴上皮瘤。后者是爱泼斯坦 - 巴尔病毒阳性，而皮肤淋巴上皮瘤样癌通常不是。皮肤淋巴上皮瘤样癌是一个需要了解的重要诊断，本文对此疾病进行了讨论。
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