Institute of Chemistry of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 48, Pervomayskaya St., Syktyvkar, 167000, Russia.
Institute of Biology of the Komi Scientific Center of Ural Branch of the RAS of FRC 'Komi SC UrB of the RAS', 28, Kommunisticheskaya St., Syktyvkar, 167982, Russia.
Chem Biodivers. 2019 Nov;16(11):e1900413. doi: 10.1002/cbdv.201900413. Epub 2019 Oct 15.
The synthesis of sulfenimines and sulfinimines has been carried out with 10-hydroxyisocamphylthiol. The configuration of the compounds has been deduced by methods of NMR, DFT calculations and X-ray diffraction analysis. The cytotoxic, antioxidant and membrane-protective activity of the synthesized compounds as well as of the previously obtained sulfenimines and sulfinimines based on 4-caranethiol have been determined.
已用 10-羟基异坎烯硫醇合成了亚磺亚胺和磺亚胺。通过 NMR、DFT 计算和 X 射线衍射分析等方法推导出了这些化合物的构型。测定了所合成的化合物以及以前基于 4-蒈烯硫醇的亚磺亚胺和磺亚胺的细胞毒性、抗氧化和膜保护活性。
