Miyauchi T, Nomura Y, Ohno S, Kishimoto H, Matsushita M
Department of Psychiatry, Yokohama City University School of Medicine, Japan.
Jpn J Psychiatry Neurol. 1988 Dec;42(4):795-804. doi: 10.1111/j.1440-1819.1988.tb01168.x.
The true responsible lesion of Lennox-Gastaut syndrome was not adequately elucidated. Three cases of this syndrome were investigated by using Positron Emission Tomography (PET). PET revealed the differences in the left and right sides, especially the hypometabolism from the frontal to temporal regions. With this finding we supposed that the L-G syndrome implies one type of partial epilepsy caused by damage in parts of the temporal or frontal lobe.
Lennox-Gastaut综合征真正的责任病灶尚未得到充分阐明。利用正电子发射断层扫描(PET)对3例该综合征患者进行了研究。PET显示左右侧存在差异,尤其是额叶至颞叶区域的代谢减低。基于这一发现,我们推测L-G综合征是由颞叶或额叶部分损伤引起的一种部分性癫痫。