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体重指数与子痫前期的关系:一项系统评价和荟萃分析。

The relationship between body mass index and preeclampsia: A systematic review and meta-analysis.

作者信息

Motedayen Morteza, Rafiei Mohammad, Rezaei Tavirani Mostafa, Sayehmiri Kourosh, Dousti Majid

机构信息

Department of Cardiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Department of Biostatistics and Epidemiology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.

出版信息

Int J Reprod Biomed. 2019 Jul 31;17(7):463-472. doi: 10.18502/ijrm.v17i7.4857. eCollection 2019 Jul.

Abstract

BACKGROUND

One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus.

OBJECTIVE

The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran.

MATERIALS AND METHODS

Using valid keywords in the SID database, PubMed, Scopus, data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and analyzed using STATA version 11.1.

RESULTS

A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m in the healthy, mild, and severe preeclamptic groups, respectively.

CONCLUSION

The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia.

摘要

背景

孕产妇和胎儿死亡及发病的原因之一是妊娠高血压,其中最常见的形式是先兆子痫,它会给母亲和胎儿带来许多并发症。

目的

本系统评价和荟萃分析的目的是确定伊朗体重指数(BMI)与先兆子痫之间的关系。

材料与方法

在SID数据库、PubMed、Scopus中使用有效关键词,将2000年至2016年在伊朗进行综述的所有文章中获得的数据,采用荟萃分析方法(随机效应模型)进行合并,并使用STATA 11.1版本进行分析。

结果

16项研究共纳入5946个样本,健康组、轻度先兆子痫组和重度先兆子痫组的平均BMI值分别为25.13、27.42和26.33kg/m²。

结论

本研究结果表明,BMI与先兆子痫风险之间存在显著关系,因此可以说BMI可能是诊断先兆子痫的方法之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f24/6718883/8cac15f45c2a/ijrb-17-463-g001.jpg

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