Knoerzer Markus, Szydzik Crispin, Ren Guanghui, Huertas Cesar S, Palmer Sonya, Tang Phuong, Nguyen Thach G, Bui Lam, Boes Andreas, Mitchell Arnan
Opt Express. 2019 Jul 22;27(15):21532-21545. doi: 10.1364/OE.27.021532.
In this contribution, we demonstrate how an optical frequency comb can be used to enhance the functionality of an integrated photonic biosensor platform. We show that if an optical frequency comb is used to sample the spectral response of a Mach-Zehnder interferometer and if the line spacing is arranged to sample the periodic response at 120° intervals, then it is possible to combine these samples into a single measurement of the interferometer phase. This phase measurement approach is accurate, independent of the bias of the interferometer and robust against intensity fluctuations that are common to each of the comb lines. We demonstrate this approach with a simple silicon photonic interferometric refractive index sensor and show that the benefits of our approach can be obtained without degrading the lower limit of detection of 3.70×10 RIU.
在本论文中,我们展示了光学频率梳如何用于增强集成光子生物传感器平台的功能。我们表明,如果使用光学频率梳对马赫-曾德尔干涉仪的光谱响应进行采样,并且将谱线间距设置为以120°间隔对周期性响应进行采样,那么就有可能将这些采样合并为干涉仪相位的单次测量。这种相位测量方法准确,与干涉仪的偏置无关,并且对每个梳状谱线常见的强度波动具有鲁棒性。我们用一个简单的硅光子干涉式折射率传感器演示了这种方法,并表明在不降低3.70×10 RIU检测下限的情况下,可以获得我们方法的益处。