Zoumpos Alexandros, Ho Ngoc Anh Huy, Loeschhorn-Becker Ralf, Schuppert Frank
Department of Gastroenterology, Endocrinology, Diabetology and General Medicine, Klinikum Kassel GmbH, Kassel, Germany.
Department of Radiology, Klinikum Kassel GmbH, Kassel, Germany.
BMJ Case Rep. 2019 Sep 11;12(9):e230454. doi: 10.1136/bcr-2019-230454.
We report on a clinical case with haemorrhagic small bowel metastases in a malignant melanoma patient with anaemia, diagnosed using small bowel video capsule endoscopy (VCE). A 67-year-old male patient with a previous diagnosis of malignant melanoma presented with anaemia and vertigo on admission. The standard diagnostic protocol for gastrointestinal (GI) bleeding investigation including a gastroscopy, colonoscopy and small bowel capsule endoscopy, as well as abdominal sonography and a restaging protocol including chest-abdomen-pelvis CT (CAP-CT), echocardiography and ECG was applied. Gastroscopy and colonoscopy were not conclusive in determining the bleeding source. VCE provided evidence for numerous haemorrhagic small bowel metastases. The CAP-CT was unremarkable for small bowel findings. Due to a diffuse metastatic disease diagnosed in heart, brain, liver, spleen and bone metastasis, the patient was treated in a conservative/palliative manner. VCE can provide precious information about GI bleeding of unknown origin when classical diagnostic methods are non-conclusive.
我们报告了一例恶性黑色素瘤患者发生出血性小肠转移瘤伴贫血的临床病例,该病例通过小肠视频胶囊内镜检查(VCE)得以确诊。一名67岁男性患者,既往诊断为恶性黑色素瘤,入院时出现贫血和眩晕症状。应用了包括胃镜、结肠镜和小肠胶囊内镜检查在内的胃肠道(GI)出血标准诊断方案,以及腹部超声检查和包括胸腹部盆腔CT(CAP-CT)、超声心动图和心电图在内的再分期方案。胃镜和结肠镜检查未能明确出血来源。VCE发现了多处出血性小肠转移瘤的证据。CAP-CT未发现小肠有明显病变。由于诊断出心脏、脑、肝、脾和骨转移的弥漫性转移性疾病,该患者接受了保守/姑息治疗。当传统诊断方法无法得出结论时,VCE可以提供有关不明原因GI出血的宝贵信息。