Beth Israel Deaconess Medical Center, Division of Pulmonary, Critical Care and Sleep Medicine, Boston, MA, United States.
Beth Israel Deaconess Medical Center, Division of Anesthesia Critical Care, Boston, MA, United States; Beth Israel Deaconess Medical Center, Department of Emergency Medicine, Boston, MA, United States.
Resuscitation. 2019 Dec;145:15-20. doi: 10.1016/j.resuscitation.2019.09.003. Epub 2019 Sep 12.
Cardiac arrest in the intensive care unit (ICU-CA) is a common and highly morbid event. We investigated the preventability of ICU-CAs and identified targets for future intervention.
This was a prospective, observational study of ICU-CAs at a tertiary care center in the United States. For each arrest, the clinical team was surveyed regarding arrest preventability. An expert, multi-disciplinary team of physicians and nurses also reviewed each arrest. Arrests were scored 0 (not at all preventable) to 5 (completely preventable). Arrests were considered 'unlikely but potentially preventable' or 'potentially preventable' if at least 50% of reviewers assigned a score of ≥1 or ≥3 respectively. Themes of preventability were assessed for each arrest.
43 patients experienced an ICU-CA and were included. A total of 14 (32.6%) and 13 (30.2%) arrests were identified as unlikely but potentially preventable by the expert panel and survey respondents respectively, and an additional 11 (25.6%) and 10 (23.3%) arrests were identified as potentially preventable. Timing of response to clinical deterioration, missed/incorrect diagnosis, timing of acidemia correction, timing of escalation to a more senior clinician, and timing of intubation were the most commonly cited contributors to potential preventability. Additional themes identified included the administration of anxiolytics/narcotics for agitation later identified to be due to clinical deterioration and misalignment between team and patient/family perceptions of prognosis and goals-of-care.
ICU-CAs may have preventable elements. Themes of preventability were identified and addressing these themes through data-driven quality improvement initiatives could potentially reduce CA incidence in critically-ill patients.
重症监护病房(ICU)中的心脏骤停是一种常见且高度病态的事件。我们研究了 ICU 心脏骤停的可预防性,并确定了未来干预的目标。
这是一项在美国一家三级医疗中心进行的 ICU 心脏骤停的前瞻性、观察性研究。对于每次心脏骤停,临床团队都会对其可预防性进行调查。一个由医生和护士组成的专家、多学科团队还会审查每次心脏骤停。心脏骤停的评分范围为 0(完全不可预防)至 5(完全可预防)。如果至少有 50%的审查者分别给予≥1 或≥3 的评分,则认为心脏骤停为“不太可能但可能可预防”或“可能可预防”。评估了每次心脏骤停的可预防性主题。
共有 43 名患者发生 ICU 心脏骤停并被纳入研究。专家小组和调查受访者分别确定了 14 例(32.6%)和 13 例(30.2%)心脏骤停为不太可能但可能可预防,另外还有 11 例(25.6%)和 10 例(23.3%)心脏骤停为可能可预防。对临床恶化的反应时间、漏诊/误诊、酸中毒纠正时间、向更高级别的临床医生升级的时间以及插管的时间是最常被认为可预防的因素。还确定了其他主题,包括为后来被认为是由于临床恶化而出现的激越而给予的镇静/麻醉剂,以及团队和患者/家属对预后和目标的看法之间存在差异。
ICU 心脏骤停可能存在可预防的因素。确定了可预防性的主题,并通过数据驱动的质量改进计划来解决这些主题,可能会降低危重症患者的心脏骤停发生率。