Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, 200241, P. R. China.
College of Pharmacy, Second Military Medical University, Shanghai, 200433, P. R. China.
Chem Commun (Camb). 2019 Sep 26;55(78):11802-11805. doi: 10.1039/c9cc05895h.
Introduction of a heteroatom into a fluorophore was carried out for coumarin through a replacement of its bridging oxygen atom with a silicon atom. The maximum-emission wavelength of Si-coumarin (SiC B) bathochromically shifted from 426 nm in cyclohexane to 626 nm in water. The adipogenic differentiation processes in mesenchymal stem cells were monitored using SiC B.
通过用硅原子取代香豆素的桥氧原子,在香豆素中引入杂原子。硅香豆素(SiC B)的最大发射波长从环己烷中的 426nm 红移到水中的 626nm。使用 SiC B 监测间充质干细胞中的脂肪生成分化过程。