间质干细胞与基质细胞：国际细胞与基因治疗学会（ISCT®）间质干细胞委员会关于命名的立场声明。
Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature.
机构信息
Arthritis Program, University Health Network, Krembil Research Institute, University Health Network, Cell Therapy Program, University Health Network, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada.
The First Affiliated Hospital, Soochow University Institutes for Translational Medicine, Suzhou, China; Institute of Health Sciences, Chinese Academy of Sciences, Shanghai, China.
出版信息
Cytotherapy. 2019 Oct;21(10):1019-1024. doi: 10.1016/j.jcyt.2019.08.002. Epub 2019 Sep 13.
The International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell (ISCT MSC) committee offers a position statement to clarify the nomenclature of mesenchymal stromal cells (MSCs). The ISCT MSC committee continues to support the use of the acronym "MSCs" but recommends this be (i) supplemented by tissue-source origin of the cells, which would highlight tissue-specific properties; (ii) intended as MSCs unless rigorous evidence for stemness exists that can be supported by both in vitro and in vivo data; and (iii) associated with robust matrix of functional assays to demonstrate MSC properties, which are not generically defined but informed by the intended therapeutic mode of actions.
国际细胞治疗学会（ISCT®）间充质基质细胞（ISCT MSC）委员会发布立场声明，以澄清间充质基质细胞（MSCs）的命名法。ISCT MSC 委员会继续支持使用缩写“MSCs”，但建议（i）补充细胞的组织来源，这将突出组织特异性特性；（ii）除非有严格的证据表明具有干细胞特性，并且可以通过体外和体内数据支持，否则将其视为 MSCs；（iii）与功能分析的强大基质相关联，以证明 MSC 特性，这些特性不是通用定义的，而是受预期治疗作用模式的影响。
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