• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Acute and chronic haloperidol treatment: comparison of effects on nigral dopaminergic cell activity.

作者信息

Bunney B S, Grace A A

出版信息

Life Sci. 1978 Oct 23;23(16):1715-27. doi: 10.1016/0024-3205(78)90471-x.

DOI:10.1016/0024-3205(78)90471-x
PMID:31529
Abstract
摘要

相似文献

1
Acute and chronic haloperidol treatment: comparison of effects on nigral dopaminergic cell activity.急性和慢性氟哌啶醇治疗:对黑质多巴胺能细胞活性影响的比较。
Life Sci. 1978 Oct 23;23(16):1715-27. doi: 10.1016/0024-3205(78)90471-x.
2
Inhibition by apomorphine of the potassium-evoked release of [3H]-gamma-aminobutyric acid from the rat substantia nigra in vitro.阿扑吗啡对体外培养的大鼠黑质中钾离子诱发的[3H] -γ-氨基丁酸释放的抑制作用。
Br J Pharmacol. 1981 Oct;74(2):389-97. doi: 10.1111/j.1476-5381.1981.tb09983.x.
3
Evidence for dopamine autoreceptors controlling dopamine synthesis in the substantia nigra.多巴胺自身受体控制黑质中多巴胺合成的证据。
Brain Res. 1982 Feb 18;234(1):177-81. doi: 10.1016/0006-8993(82)90484-x.
4
Zetidoline, a novel neuroleptic, activates nigral dopaminergic neurons in rats.泽替多林是一种新型抗精神病药物,可激活大鼠黑质多巴胺能神经元。
Life Sci. 1985 Feb 4;36(5):459-64. doi: 10.1016/0024-3205(85)90258-9.
5
[Effect of intracaudate administration of kainic acid on the activity of the dopaminergic system].[尾状核内注射 kainic 酸对多巴胺能系统活性的影响]
Fiziol Zh SSSR Im I M Sechenova. 1981 Nov;67(11):1606-10.
6
Study of the morphological, electrophysiological and behavioral effects of unilateral kainic acid injection into the cat's substantia nigra.单侧向猫黑质注射海人酸的形态学、电生理学及行为学效应研究
Brain Res. 1987 Mar 3;405(1):165-8. doi: 10.1016/0006-8993(87)91002-x.
7
Function of nigral dopamine receptors?黑质多巴胺受体的功能?
Brain Res. 1978 Nov 10;156(2):380-1. doi: 10.1016/0006-8993(78)90523-1.
8
Biphasic and opposite effects of dopamine and apomorphine on endogenous GABA release in the rat substantia nigra.多巴胺和阿扑吗啡对大鼠黑质内源性γ-氨基丁酸释放的双相及相反作用。
J Neurochem. 1980 Jan;34(1):119-25. doi: 10.1111/j.1471-4159.1980.tb04629.x.
9
Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording.反复给予氟哌啶醇诱导中脑多巴胺神经元去极化阻滞:运用体内细胞内记录法进行分析
J Pharmacol Exp Ther. 1986 Sep;238(3):1092-100.
10
Comparative effects of chronic haloperidol and sulpiride treatment on nigral and striatal GABA content.慢性氟哌啶醇和舒必利治疗对黑质和纹状体γ-氨基丁酸含量的比较影响。
J Neurochem. 1981 Oct;37(4):1048-51. doi: 10.1111/j.1471-4159.1981.tb04495.x.

引用本文的文献

1
Combination Lorcaserin and Betahistine Treatment Improves Cognitive Dysfunction and Dopaminergic Neuron Activity in a Rat Model of Diet-Induced Obesity.联合使用氯卡色林和倍他司汀治疗可改善饮食诱导肥胖大鼠模型中的认知功能障碍和多巴胺能神经元活性。
Brain Sci. 2025 Aug 25;15(9):913. doi: 10.3390/brainsci15090913.
2
Cranial radiation disrupts dopaminergic signaling and connectivity in the mammalian brain.颅脑放疗会破坏哺乳动物大脑中的多巴胺能信号传导和连接。
Acta Neuropathol Commun. 2025 Mar 13;13(1):59. doi: 10.1186/s40478-025-01976-3.
3
The antipsychotic agent sulpiride microinjected into the ventral pallidum restores positive symptom-like habituation disturbance in MAM-E17 schizophrenia model rats.
腹侧苍白球内注射抗精神病药物舒必利可恢复 MAM-E17 精神分裂症模型大鼠阳性症状样习惯化障碍。
Sci Rep. 2024 May 29;14(1):12305. doi: 10.1038/s41598-024-63059-y.
4
Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo.多巴胺信号增强的纹状体基因集可预测纹状体多巴胺合成和体内生理活性。
Nat Commun. 2024 Apr 30;15(1):3342. doi: 10.1038/s41467-024-47456-5.
5
Insights into the Mechanism of Action of Antipsychotic Drugs Derived from Animal Models: Standard of Care versus Novel Targets.从动物模型看抗精神病药物作用机制:标准治疗与新靶点。
Int J Mol Sci. 2023 Aug 3;24(15):12374. doi: 10.3390/ijms241512374.
6
Increased Presynaptic Dopamine Synthesis Capacity Is Associated With Aberrant Dopamine Neuron Activity in the Methylazoxymethanol Acetate Rodent Model Used to Study Schizophrenia-Related Pathologies.在用于研究精神分裂症相关病理的醋酸甲基氧化偶氮甲醇啮齿动物模型中,突触前多巴胺合成能力增强与多巴胺神经元活动异常有关。
Schizophr Bull Open. 2022 Oct 21;3(1):sgac067. doi: 10.1093/schizbullopen/sgac067. eCollection 2022 Jan.
7
Using animal models for the studies of schizophrenia and depression: The value of translational models for treatment and prevention.使用动物模型研究精神分裂症和抑郁症:转化模型在治疗与预防方面的价值。
Front Behav Neurosci. 2022 Aug 24;16:935320. doi: 10.3389/fnbeh.2022.935320. eCollection 2022.
8
Dopamine D2-Subtype Receptors Outside the Blood-Brain Barrier Mediate Enhancement of Mesolimbic Dopamine Release and Conditioned Place Preference by Intravenous Dopamine.血脑屏障外的多巴胺D2亚型受体介导静脉注射多巴胺增强中脑边缘多巴胺释放及条件性位置偏爱。
Front Cell Neurosci. 2022 Jul 12;16:944243. doi: 10.3389/fncel.2022.944243. eCollection 2022.
9
Medial septum activation improves strategy switching once strategies are well-learned via bidirectional regulation of dopamine neuron population activity.内侧隔激活通过双向调节多巴胺神经元群体活动,改善了策略习得后的策略切换。
Neuropsychopharmacology. 2022 Nov;47(12):2090-2100. doi: 10.1038/s41386-022-01387-1. Epub 2022 Jul 23.
10
The Arousal-motor Hypothesis of Dopamine Function: Evidence that Dopamine Facilitates Reward Seeking in Part by Maintaining Arousal.多巴胺功能的觉醒-运动假说:多巴胺通过维持觉醒来促进奖励寻求的证据。
Neuroscience. 2022 Sep 1;499:64-103. doi: 10.1016/j.neuroscience.2022.07.008. Epub 2022 Jul 16.