Zhu Ming-Yu, Sun Li-Qun
Critical Care Unit, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China.
World J Clin Cases. 2019 Aug 26;7(16):2360-2366. doi: 10.12998/wjcc.v7.i16.2360.
Severe total colonic necrosis, septic shock and venous thromboembolism secondary to ulcerative colitis (UC) are rare and life-threatening. No such severe complications have been reported in the literature.
We report a 36-year-old woman who developed total colonic necrosis and septic shock secondary to UC. The patient was treated with emergency surgery because computed tomography showed suspicious perforations. Persistent massive ascites occurred after operation and computed tomography angiography demonstrated portal vein, mesenteric vein and splenic vein thrombosis. The patient was discharged from hospital after active treatment.
Clinicians should pay attention to venous thrombosis, colonic necrosis and septic shock in UC patients. Close observation of surgical indications and timely surgical intervention are the key to reduce mortality and complications in UC.
溃疡性结肠炎(UC)继发严重全结肠坏死、感染性休克和静脉血栓栓塞罕见且危及生命。文献中未报道过此类严重并发症。
我们报告一名36岁女性,继发于UC出现全结肠坏死和感染性休克。因计算机断层扫描显示可疑穿孔,患者接受了急诊手术。术后持续出现大量腹水,计算机断层扫描血管造影显示门静脉、肠系膜静脉和脾静脉血栓形成。经过积极治疗,患者出院。
临床医生应关注UC患者的静脉血栓形成、结肠坏死和感染性休克。密切观察手术指征并及时进行手术干预是降低UC死亡率和并发症的关键。