糙皮病与神经性厌食症：一例报告
Pellagra and anorexia nervosa: a case report.
作者信息
Portale Sandra, Sculati Michele, Stanford Fatima Cody, Cena Hellas
机构信息
Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Bassi 21, 27100, Pavia, PV, Italy.
Department of Public Health, Experimental and Forensic Medicine, Master Course in Dietetics and Clinical Nutrition, University of Pavia, Via Bassi 21, 27100, Pavia, PV, Italy.
出版信息
Eat Weight Disord. 2020 Oct;25(5):1493-1496. doi: 10.1007/s40519-019-00781-x. Epub 2019 Sep 17.
BACKGROUND
While pellagra appears to be a rare entity currently, it may still develop. It is important to recognize how the disease manifests to ensure adequate and timely treatment.
CASE PRESENTATION
We present a case of pellagra secondary to anorexia nervosa in a 28-year-old woman. We observed the classical signs: erythema in the neck region, diarrhea, and neurologic symptoms. Diagnosis was made on a clinical basis, and the patient had a rapid recovery after undergoing therapy with nicotinamide and tryptophan.
CONCLUSIONS
In our case, the patient did not exhibit any sign of being severely underweight with marked malnutrition such as the typical manifestation expected in pellagra. This case demonstrated that clinicians should have a high level of suspicion in making a diagnosis of pellagra, especially in patients with a history of eating disorders.
LEVEL OF EVIDENCE
IV (case study).
背景
虽然糙皮病目前似乎是一种罕见疾病，但仍可能发生。认识到该疾病的表现形式对于确保充分和及时的治疗很重要。
病例报告
我们报告一例28岁女性因神经性厌食继发糙皮病的病例。我们观察到了典型症状：颈部红斑、腹泻和神经症状。诊断基于临床情况做出，患者在接受烟酰胺和色氨酸治疗后迅速康复。
结论
在我们的病例中，患者没有表现出任何严重体重不足和明显营养不良的迹象，而这是糙皮病的典型表现。该病例表明，临床医生在诊断糙皮病时应保持高度怀疑，尤其是对于有饮食失调病史的患者。
证据级别
IV（病例研究）。
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