Fukushima Kazuaki, Yanagisawa Naoki, Sekiya Noritaka, Izumiya Hidemasa
Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital, Japan.
Bureau of International Health Cooperation, National Center for Global Health and Medicine, Japan.
Intern Med. 2020 Jan 15;59(2):289-292. doi: 10.2169/internalmedicine.3161-19. Epub 2019 Sep 18.
Non-typhoidal Salmonella (NTS) infection is a major pathogen causing gastroenteritis among immunocompetent adults. NTS infection is mainly transmitted by contaminated food and water, but some cases are transmitted by animal contact. Salmonella enterica subsp. enterica serovar Poona (S. Poona) is an NTS usually transmitted by reptiles, and cases including outbreaks of gastroenteritis have been reported previously. However, invasive infections due to this organism among immunocompetent adults are rare. We herein report a case of a 39-year-old man who was admitted to our hospital for a fever and headache. Blood cultures were positive for S. Poona, although he did not recall any exposure to reptiles. He was treated successfully with intravenous ceftriaxone without any subsequent complications. This case implies that NTS bacteremia can occur in immunocompetent adults, and the diagnosis may be challenging since there may be no clear exposure or focal physical signs.
非伤寒沙门氏菌（NTS）感染是免疫功能正常的成年人中引起肠胃炎的主要病原体。NTS感染主要通过受污染的食物和水传播，但有些病例是通过与动物接触传播的。肠炎沙门氏菌肠炎亚种浦那血清型（S. Poona）是一种通常由爬行动物传播的NTS，此前已有包括肠胃炎暴发在内的病例报道。然而，这种微生物在免疫功能正常的成年人中引起的侵袭性感染很少见。我们在此报告一例39岁男性患者，因发热和头痛入院。血培养显示浦那沙门氏菌阳性，尽管他不记得有任何接触爬行动物的经历。他接受了静脉注射头孢曲松治疗，治疗成功，无任何后续并发症。该病例表明，免疫功能正常的成年人也可能发生NTS菌血症，且由于可能没有明确的接触史或局部体征，诊断可能具有挑战性。
