Chang Chen, Jin Wen Zhang, Dan Chen, Chun Ming Guo, and Jun Zhang are with the Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Hui Xin Zhang is with the Department of Obstetrics, Fourth Hospital of Hebei Medical University, Hebei, China. Ana Pilar Betran is with the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, and Department of Reproductive Health and Research, World Health Organization (WHO), Geneva, Switzerland. Lin Zhang and Xiao Lin Hua are with the Department of Obstetrics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine. Li Ping Feng is with the Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC. Kang Sun is with the Center for Reproductive Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine. Hong Bo Qi is with the Department of Obstetrics and Gynecology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Tao Duan is with the Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai.
Am J Public Health. 2019 Nov;109(11):1597-1604. doi: 10.2105/AJPH.2019.305287. Epub 2019 Sep 19.
To describe the incidence, risk factors, and potential causes of preterm birth (PTB) in China between 2015 and 2016. The China Labor and Delivery Survey was a population-based multicenter study conducted from 2015 to 2016. We assigned each birth a weight based on the sampling frame. We calculated the incidence of PTB and the multivariable logistic regression, and we used 2-step cluster analysis to examine the relationships between PTB and maternal, fetal, and placental conditions. The weighted nationwide incidence of PTB was 7.3% of all births and 6.7% of live births at 24 or more weeks of gestation. Of the PTBs, 70.5% were born after 34 weeks and 42.7% were iatrogenic. Nearly two thirds of all preterm births were attributable to maternal, fetal, or placental conditions, and one third had unknown etiology. This study provided information on the incidence of PTB in China and identified several factors associated with PTB. The high frequency of iatrogenic PTB calls for a careful assessment and prudent management of such pregnancies, as PTB has short- and long-term health consequences.
描述 2015 年至 2016 年中国早产（PTB）的发生率、风险因素和潜在原因。中国分娩调查是一项基于人群的多中心研究，于 2015 年至 2016 年进行。我们根据抽样框架为每个分娩分配权重。我们计算了 PTB 的发生率和多变量逻辑回归，并使用两步聚类分析来检查 PTB 与母婴、胎儿和胎盘状况之间的关系。全国加权早产发生率为所有分娩的 7.3%，24 周或以上活产的 6.7%。在这些 PTB 中，70.5%是在 34 周后出生的，42.7%是医源性的。近三分之二的所有早产归因于母婴、胎儿或胎盘状况，三分之一的早产病因不明。本研究提供了中国 PTB 发生率的信息，并确定了与 PTB 相关的几个因素。医源性 PTB 的高频率需要对这些妊娠进行仔细评估和谨慎管理，因为 PTB 有短期和长期的健康后果。
