Bij de Weg Jeske M, de Groot Christianne J, Pajkrt Eva, de Boer Marjon A
Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
BMJ Case Rep. 2019 Sep 18;12(9):e227667. doi: 10.1136/bcr-2018-227667.
Women with a multiple pregnancy are at increased risk of developing hypertensive disorders of pregnancy. We describe a case of a dichorionic triamniotic triplet pregnancy complicated by severe hypertension, proteinuria and maternal symptoms, fitting with the diagnosis of pre-eclampsia, apart from the early gestational age of only 16 weeks. After reduction of the monochorionic pair, the disease resolved and pre-eclampsia was diagnosed again at 30 weeks of gestation, resulting in a delivery on maternal indication at 33 weeks of gestation. In a review of the literature, we found six papers including eight cases on multifetal pregnancy reduction on maternal indication. Multifetal pregnancy reduction resulted in a prolongation of pregnancy of two to 21 weeks and may be considered in extreme early onset pre-eclampsia in dichorionic multiple pregnancies.
多胎妊娠的女性发生妊娠高血压疾病的风险增加。我们描述了一例双绒毛膜三羊膜囊三胎妊娠病例,该病例合并严重高血压、蛋白尿及母体症状,除孕周仅16周较早外,符合子痫前期的诊断。在减灭单绒毛膜双胎后,病情缓解,妊娠30周时再次诊断为子痫前期,因母体指征于妊娠33周分娩。在文献回顾中,我们发现6篇论文,包括8例因母体指征行多胎妊娠减胎术的病例。多胎妊娠减胎术使孕周延长了2至21周,对于双绒毛膜多胎妊娠极早发子痫前期可考虑采用该方法。