Private practice, Milan, Italy.
Italian Health Ministry, Rome, Italy.
J Biol Regul Homeost Agents. 2019 May-Jun;33(3 Suppl. 1):113-119. DENTAL SUPPLEMENT.
Cardiovascular disease (CVD) is a common cause of death, representing 29% of the mortality all over the word. Estimates for 2006 show that CVD is one of the world's main cause of death, with 17.1 million death per year. More than 70 million Americans have been diagnosed with various forms of CVD, including high blood pressure, coronary artery disease (acute myocardial infarction and angina pectoris), disorders of peripheral arteries etc. There is strong evidence that periodontal disease (PD) is associated with an increased risk of CVD. In addiction many patients with CVD are also affected by PD, which can be mild or severe. The aim of this manuscript is to investigate the effects of periodontal therapy on the management of CVD. 34 randomised controlled trials and reviews were included in this manuscript to test the effects of different periodontal therapies for patients with CVD. In conclusion, we may affirm that there is some lack of knowledge on relations between PD and CVD, however there is sufficient evidence to justify a periodontal treatment to prevent CVD, in fact PD is very prevalent in middle-aged population and can have a significant impact on the cardiovascular function.
心血管疾病（CVD）是一种常见的死亡原因，占全球所有死亡人数的 29%。2006 年的估计显示，心血管疾病是世界上主要的死亡原因之一，每年有 1710 万人死亡。超过 7000 万美国人被诊断患有各种形式的心血管疾病，包括高血压、冠状动脉疾病（急性心肌梗死和心绞痛）、外周动脉疾病等。有强有力的证据表明，牙周病（PD）与心血管疾病的风险增加有关。此外，许多患有 CVD 的患者也患有 PD，其严重程度不一。本文的目的是探讨牙周治疗对 CVD 管理的影响。本文纳入了 34 项随机对照试验和综述，以检验不同牙周治疗方法对 CVD 患者的疗效。总之，我们可能会发现 PD 和 CVD 之间的关系还存在一些知识上的欠缺，但有充分的证据证明牙周治疗可以预防 CVD，事实上 PD 在中年人群中非常普遍，并且会对心血管功能产生重大影响。
