Breast Cancer Center, Hospital São Lucas, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Breast Cancer Group, Albert Einstein Hospital, São Paulo, Brazil.
Breast J. 2020 Mar;26(3):427-432. doi: 10.1111/tbj.13502. Epub 2019 Sep 20.
The aim of this study was to evaluate 10-year local control and overall survival of IORT for early breast cancer treatment. We analyzed 68 patients submitted to breast conservative surgery and IORT, in the accelerator room of the Radiotherapy Service in South Brazil. In the long-term follow-up, we had 17.6% of patients with ipsilateral breast cancer recurrence, 2.9% with regional recurrence, 2.9% with contralateral breast recurrence, and 5.9% with distant metastasis. The 10-year overall survival was 82.8%. Our data show high local recurrence rates, however, good overall survival in early breast cancer patients treated with breast-conserving surgery and intraoperative radiotherapy with electron beams in the long-term follow-up.
本研究旨在评估术中放疗（IORT）治疗早期乳腺癌的 10 年局部控制率和总生存率。我们分析了 68 例在巴西南部放射治疗服务中心加速器室内接受保乳手术和 IORT 的患者。在长期随访中，我们有 17.6%的患者同侧乳房癌症复发，2.9%的患者区域复发，2.9%的患者对侧乳房癌症复发，5.9%的患者远处转移。10 年总生存率为 82.8%。我们的数据显示局部复发率较高，但在长期随访中，采用保乳手术和电子束术中放疗治疗的早期乳腺癌患者总体生存率良好。
