Kiss Zoltán, Berki Tamás László, Maráz Anikó, Horváth Zsolt, Nagy Péter, Fábián Ibolya, Kovács Valéria, Rokszin György, Surján György, Barcza Zsófia, Kenessey István, Wéber András, Wittmann István, Molnár Gergő Attila, Szabó Tamás G, Buga Viktória, Karamousouli Eugenia, Darida Miklós, Abonyi-Tóth Zsolt, Bertókné Tamás Renáta, Fürtős Viktória Diána, Bogos Krisztina, Moldvay Judit, Gálffy Gabriella, Tamási Lilla, Müller Veronika, Krasznai Zoárd Tibor, Ostoros Gyula, Pápai-Székely Zsolt, Branyiczkiné Géczy Gabriella, Hilbert Lászlóné, Polgár Csaba, Vokó Zoltán
MSD Pharma Hungary Ltd., 1095 Budapest, Hungary.
Second Department of Medicine and Nephrology-Diabetes Centre, University of Pécs Medical School, 7624 Pécs, Hungary.
Cancers (Basel). 2025 May 15;17(10):1670. doi: 10.3390/cancers17101670.
Assessing cancer survival trends is crucial for monitoring progress in cancer management and prevention. As part of the broader HUN-CANCER EPI study, this analysis examined overall survival (OS) in the Hungarian cancer population between 2011 and 2019. Using data extracted from the Hungarian National Health Insurance Fund (NHIF) database, short- and long-term OS were estimated for various cancer types according to age, sex, and diagnostic period using Kaplan-Meier analysis. The study also identified cancer types with significant early mortality following diagnosis. From 2011 to 2019, a total of 528,808 patients were diagnosed with cancer. During the 2015-2019 diagnostic period, the lowest 5-year OS rates were observed for esophageal (7.0%), pancreatic (10.7%), liver (12.5%), gallbladder (13.9%), and lung cancer (18.4%). Conversely, tumor types with better OS included testicular cancer (91.6%), thyroid cancer (89.0%), Hodgkin's lymphoma (84.0%), melanoma (78.6%), and breast cancer (74.1%). A notable proportion of deaths occurred within 2 months of diagnosis for liver (33.2%), pancreatic (27.9%), and gallbladder cancer (29.0%). Significant early mortality within 6 months post-diagnosis was also noted for esophageal (51.3%), stomach (42.9%), and lung cancer (41.7%). The HUN-CANCER EPI study conducted between 2011 and 2019 provides valuable insights into cancer survival patterns in Hungary, emphasizing the importance of early detection and targeted interventions to improve patient outcomes.
评估癌症生存趋势对于监测癌症管理和预防方面的进展至关重要。作为更广泛的匈牙利癌症流行病学(HUN-CANCER EPI)研究的一部分,本分析考察了2011年至2019年匈牙利癌症患者群体的总生存期(OS)。利用从匈牙利国家健康保险基金(NHIF)数据库提取的数据,采用Kaplan-Meier分析法,根据年龄、性别和诊断时期,对各种癌症类型的短期和长期总生存期进行了估计。该研究还确定了诊断后早期死亡率较高的癌症类型。2011年至2019年期间,共有528,808名患者被诊断患有癌症。在2015 - 2019年诊断期间,观察到食管癌(7.0%)、胰腺癌(10.7%)、肝癌(12.5%)、胆囊癌(13.9%)和肺癌(18.4%)的5年总生存率最低。相反,总生存期较好的肿瘤类型包括睾丸癌(91.6%)、甲状腺癌(89.0%)、霍奇金淋巴瘤(84.0%)、黑色素瘤(78.6%)和乳腺癌(74.1%)。相当比例的死亡发生在肝癌(33.2%)、胰腺癌(27.9%)和胆囊癌(29.0%)诊断后的2个月内。食管癌(51.3%)、胃癌(42.9%)和肺癌(41.7%)在诊断后6个月内也出现了显著的早期死亡率。2011年至2019年进行的匈牙利癌症流行病学(HUN-CANCER EPI)研究为匈牙利的癌症生存模式提供了有价值的见解,强调了早期检测和针对性干预对改善患者预后的重要性。