Drissa Meriem, Helali Sana, Amani Farah, Chebbi Marwa, Mechri Mehdi, Drissa Habiba
Tunis Med. 2019 Feb;97(2):373-378.
Echocardiography is a non invasive tool for the assessment of systemic lupus erythematesus (SLE) involvement .
to investigate the cardiac involvement in patients diagnosed with SLE assessed by echocardiography and to study relationship between several factors and cardiac manifestation .
retrospective study of 76 patients with diagnosis of SLE between 2008 and 2017. All patients were asssesed by echocardiography .Patients were assigned into cardiac abnormalities group and non cardiac abnormmalties and compared to study relations between several factors and cardiac manifestation .
Cardiac involvement was found in echocardiography in 52% of patients (40 patients. Echocardiographic findings showed 12 cases ( 38 %) of pericardial effusion . Valvular abnormalities were observed in 19 cases (48 %), Myocardium was involved in 5 cases ( 12.5 %). there were no cases of myocarditis , High arterial pulmonary hypertension was reported in 4 cases (10%). Men were more vulnerable to cardiac involvement in lupus , there was signifiant relationship between disease duration and cardiac abnormalities (p 0.04 ), age was not associated significantly to echocardiographic abnormalites ,positif antiphospholipid antibodies(aPL+) was observed in higher frequency in cardiac involvement group with p<0.01 and especially in valvular anomalies Conclusion : Echocardiography should be routinely indicated for evaluation of cardiac involvement during SLE. These manifestations are most often moderate and asymptomatic. Pericardial effusion, and valvular involvement were the most frequent abnormalities.
超声心动图是评估系统性红斑狼疮(SLE)累及情况的一种非侵入性工具。
通过超声心动图研究确诊为SLE的患者的心脏受累情况,并研究若干因素与心脏表现之间的关系。
对2008年至2017年间诊断为SLE的76例患者进行回顾性研究。所有患者均接受超声心动图检查。将患者分为心脏异常组和非心脏异常组,并进行比较,以研究若干因素与心脏表现之间的关系。
超声心动图检查发现52%的患者(40例)存在心脏受累。超声心动图检查结果显示,12例(38%)有心包积液。观察到19例(48%)有瓣膜异常,5例(12.5%)有心肌受累。无心肌炎病例,4例(10%)报告有高动脉性肺动脉高压。男性在狼疮中更易发生心脏受累,病程与心脏异常之间存在显著关系(p<0.04),年龄与超声心动图异常无显著相关性,抗磷脂抗体阳性(aPL+)在心脏受累组中的出现频率更高,p<0.01,尤其是在瓣膜异常中。结论:超声心动图应常规用于评估SLE期间的心脏受累情况。这些表现大多为中度且无症状。心包积液和瓣膜受累是最常见的异常情况。