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儿童后颅窝肿瘤:基因组肿瘤分类和先进磁共振技术时代的放射学技巧与窍门。

Posterior fossa tumors in children: Radiological tips & tricks in the age of genomic tumor classification and advance MR technology.

机构信息

Department of Pediatric Radiology, Clocheville University Hospital, CHRU Tours, Tours, France; Department of Neuroradiology, Bretonneau University Hospital, CHRU Tours, Tours, France.

Department of Neuroradiology, Bretonneau University Hospital, CHRU Tours, Tours, France; Faculty of Medicine, Francois-Rabelais University, Tours, France.

出版信息

J Neuroradiol. 2020 Feb;47(1):46-53. doi: 10.1016/j.neurad.2019.08.002. Epub 2019 Sep 18.

DOI:10.1016/j.neurad.2019.08.002
PMID:31541639
Abstract

Imaging plays a major role in the comprehensive assessment of posterior fossa tumor in children (PFTC). The objective is to propose a global method relying on the combined analysis of radiological, clinical and epidemiological criteria, (taking into account the child's age and the topography of the lesion) in order to improve our histological approach in imaging, helping the management and approach for surgeons in providing information to the patients' parents. Infratentorial tumors are the most frequent in children, representing mainly medulloblastoma, pilocytic astrocytoma and brainstem glioma. Pre-surgical identification of the tumor type and its aggressiveness could be improved by the combined analysis of key imaging features with epidemiologic data.

摘要

影像学在儿童后颅窝肿瘤(PFTC)的综合评估中起着重要作用。目的是提出一种基于放射学、临床和流行病学标准综合分析的全局方法(考虑到儿童的年龄和病变的部位),以改善我们在影像学中的组织学方法,帮助外科医生为患者家长提供信息,指导治疗。儿童中最常见的是小脑肿瘤,主要包括髓母细胞瘤、毛细胞星形细胞瘤和脑干胶质瘤。通过关键影像学特征与流行病学数据的综合分析,可以提高术前对肿瘤类型及其侵袭性的识别。

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