Setyawan Nurhuda Hendra, Hartanto Rachmat Andi, Malueka Rusdy Ghazali, Dwianingsih Ery Kus, Dharma Dito Pondra
Department of Radiology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, Indonesia.
Department of Surgery, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, Indonesia.
Radiol Case Rep. 2024 Aug 17;19(11):5000-5006. doi: 10.1016/j.radcr.2024.07.158. eCollection 2024 Nov.
Hemangioblastomas are rare, benign, and highly vascular tumors of the central nervous system, often associated with von Hippel-Lindau (VHL) syndrome, an autosomal dominant disorder characterized by multiple tumors. We present a case of a 32-year-old male with progressive headaches, visual disturbances, and motor deficits, who was diagnosed with multiple hemangioblastomas in the cervical-thoracic spinal cord and bilateral cerebellum through MRI. Surgical resection and histopathological biopsy confirmed the diagnosis. This case highlights the critical role of MRI in diagnosing and managing VHL-associated hemangioblastomas and underscores the importance of regular imaging for early detection and intervention of new or recurring tumors, optimizing patient outcomes.
血管母细胞瘤是中枢神经系统罕见的良性高血管性肿瘤,常与冯·希佩尔-林道(VHL)综合征相关,VHL综合征是一种以多发性肿瘤为特征的常染色体显性疾病。我们报告一例32岁男性患者,有进行性头痛、视觉障碍和运动功能缺损,通过磁共振成像(MRI)诊断为颈胸段脊髓和双侧小脑多发血管母细胞瘤。手术切除及组织病理学活检确诊。该病例突出了MRI在诊断和管理VHL相关血管母细胞瘤中的关键作用,并强调了定期成像对于早期发现和干预新的或复发性肿瘤、优化患者预后的重要性。