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面向癌症患者及幸存者的临床试验参与动画。

Animations about Clinical Trial Participation for Cancer Patients and Survivors.

作者信息

Occa Aurora, Morgan Susan E

机构信息

Department of Communication, University of Kentucky, Lexington, Kentucky, USA.

Department of Communication Studies, University of Miami, Coral Gables, Florida, USA.

出版信息

J Health Commun. 2019;24(10):749-760. doi: 10.1080/10810730.2019.1668089. Epub 2019 Sep 21.

DOI:10.1080/10810730.2019.1668089
PMID:31543072
Abstract

Communicating about clinical trials and medical research is challenging. An appropriate communication is essential to reduce some of the barriers associated with poor patients' enrollment in clinical trials and with patients' uninformed consent or uninformed refusal. An experiment was conducted to assess the effects of educational animations compared to brochures with and without visuals, and with the materials currently used by the NIH. These materials focused on explaining placebos, randomization, the steps necessary to enroll in a clinical trial, and how and by who patients' protection is ensured. A total of 1194 cancer patients and survivors completed this 4 by 4 experiment through a Qualtrics panel. The findings showed that animations improved participants knowledge about and attitudes toward clinical trials and were more effective than brochures presenting information from the NIH, especially for those individuals with low motivation and low ability to comprehend health-related information. Several evidence-based theoretical explanations of the functioning of animations are provided.

摘要

就临床试验和医学研究进行沟通具有挑战性。恰当的沟通对于减少一些与临床试验患者招募不佳以及患者不知情同意或不知情拒绝相关的障碍至关重要。进行了一项实验,以评估教育动画与有视觉效果和无视觉效果的宣传册以及美国国立卫生研究院(NIH)目前使用的材料相比的效果。这些材料着重解释安慰剂、随机化、参与临床试验所需的步骤,以及如何确保患者得到保护以及由谁来确保。共有1194名癌症患者和幸存者通过Qualtrics面板完成了这个4×4实验。研究结果表明,动画提高了参与者对临床试验的了解和态度,并且比展示NIH信息的宣传册更有效,尤其是对于那些积极性低且理解健康相关信息能力低的个体。文中提供了关于动画作用的几种基于证据的理论解释。

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