Hanumaiah Bangaru, Joseph Joice Maria
Department of Skin and VD, Mysore Medical College and Research Institute, Mysore, Karnataka, India.
Indian J Dermatol. 2019 Sep-Oct;64(5):341-345. doi: 10.4103/ijd.IJD_123_18.
A dermoscope is an office tool used in the diagnosis of various disorders. At present, studies on hypertrophic lichen planus (HLP) and prurigo nodularis (PN) are limited.
The aim of this study was to compare the dermoscopic features of HLP and PN and to determine the role of dermoscopy in the differential diagnosis of both the conditions.
A cross-sectional study was undertaken. After clinical assessment and relevant investigations, dermoscopy was performed using DermLite DL3 dermoscope (×10) followed by histopathology. Dermoscopic findings in cases of HLP and PN were evaluated.
Thirty patients each with HLP and PN were included in the study. On dermoscopy, peripheral striations were the most common findings in both the conditions. Statistically significant features on intergroup comparison included blue-gray globules (<0.001), comedo-like openings (<0.001), and follicular plugging (<0.001) in HLP and pearly white areas with white starburst pattern (=0.028), red dots and globules (<0.001), glomerular vessels (=0.003), crusting (=0.002), and erosions (<0.001) in PN.
Dermoscopy is useful in differentiating HLP and PN. Blue-gray globules, comedo-like openings, and follicular plugging were specific for HLP. Pearly white areas with white starburst pattern and red dots and globules were the specific findings in PN.
皮肤镜是一种用于诊断各种疾病的门诊工具。目前，关于肥厚性扁平苔藓（HLP）和结节性痒疹（PN）的研究有限。
本研究旨在比较HLP和PN的皮肤镜特征，并确定皮肤镜在这两种疾病鉴别诊断中的作用。
进行了一项横断面研究。经过临床评估和相关检查后，使用DermLite DL3皮肤镜（×10）进行皮肤镜检查，随后进行组织病理学检查。对HLP和PN病例的皮肤镜检查结果进行评估。
本研究纳入了30例HLP患者和30例PN患者。在皮肤镜检查中，周边条纹是这两种疾病最常见的表现。组间比较具有统计学意义的特征包括HLP中的蓝灰色小球（<0.001）、粉刺样开口（<0.001）和毛囊堵塞（<0.001），以及PN中的珍珠白色区域伴白色星芒状图案（=0.028）、红点和小球（<0.001）、肾小球样血管（=0.003）、结痂（=0.002）和糜烂（<0.001）。
皮肤镜有助于鉴别HLP和PN。蓝灰色小球、粉刺样开口和毛囊堵塞是HLP的特异性表现。珍珠白色区域伴白色星芒状图案以及红点和小球是PN的特异性表现。
