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AIDS Behav. 2014 Oct;18(10):1864-87. doi: 10.1007/s10461-014-0827-7.
2
Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.博茨瓦纳异性传播 HIV 中抗逆转录病毒的预先暴露预防。
N Engl J Med. 2012 Aug 2;367(5):423-34. doi: 10.1056/NEJMoa1110711. Epub 2012 Jul 11.
3
Risk and protective factors for depression symptoms among children affected by HIV/AIDS in rural China: a structural equation modeling analysis.中国农村地区受 HIV/AIDS 影响儿童的抑郁症状的风险和保护因素:结构方程模型分析。
Soc Sci Med. 2012 May;74(9):1435-43. doi: 10.1016/j.socscimed.2012.01.007. Epub 2012 Feb 25.
4
Determinants of per-coital-act HIV-1 infectivity among African HIV-1-serodiscordant couples.非洲 HIV-1 血清不一致的夫妇中单次性行为 HIV-1 感染性的决定因素。
J Infect Dis. 2012 Feb 1;205(3):358-65. doi: 10.1093/infdis/jir747. Epub 2012 Jan 11.
5
Factors influencing quality of life among people living with HIV (PLWH) in Suphanburi Province, Thailand.影响泰国素攀武里府艾滋病毒感染者(PLWH)生活质量的因素。
J Assoc Nurses AIDS Care. 2012 Jan-Feb;23(1):63-72. doi: 10.1016/j.jana.2011.01.003. Epub 2011 Apr 15.
6
[Living with the difference: the impact of serodiscordance on the affective and sexual life of HIV/AIDS patients].《与差异共处:血清学不一致对艾滋病毒/艾滋病患者情感和性生活的影响》
Rev Esc Enferm USP. 2010 Sep;44(3):759-65. doi: 10.1590/s0080-62342010000300030.
7
An overview of the relative risks of different sexual behaviours on HIV transmission.不同性行为导致 HIV 传播的相对风险概述。
Curr Opin HIV AIDS. 2010 Jul;5(4):291-7. doi: 10.1097/COH.0b013e32833a88a3.
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Benefits of family and social relationships for Thai parents living with HIV.泰国家庭中艾滋病毒感染者父母的家庭和社会关系的益处。
Prev Sci. 2010 Sep;11(3):298-307. doi: 10.1007/s11121-009-0165-6.
9
[Analyzing the risk problem in couples with serodiscordance].[分析血清学不一致夫妇中的风险问题]
Cien Saude Colet. 2008 Nov-Dec;13(6):1859-68. doi: 10.1590/s1413-81232008000600021.
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HIV/AIDS and maternity care in Kenya: how fears of stigma and discrimination affect uptake and provision of labor and delivery services.肯尼亚的艾滋病毒/艾滋病与孕产妇保健:对耻辱和歧视的恐惧如何影响分娩服务的接受和提供。
AIDS Care. 2008 Sep;20(8):938-45. doi: 10.1080/09540120701767224.

一项分析血清学不一致伴侣间社会、性及生殖方面挑战的横断面研究。

A Cross-sectional Study to Analyze the Social, Sexual, and Reproductive Challenges among Serodiscordant Couples.

作者信息

Saraswat Neerja, Chopra Ajay, Kumar Sushil, Agarwal Reetu, Mitra Debdeep, Kamboj Parul

机构信息

Department of Dermatology, Base Hospital, New Delhi, India.

Department of Dermatology, MLN Medical College, Allahabad, Uttar Pradesh, India.

出版信息

Indian J Dermatol. 2019 Sep-Oct;64(5):377-382. doi: 10.4103/ijd.IJD_367_18.

DOI:10.4103/ijd.IJD_367_18
PMID:31543532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6749756/
Abstract

INTRODUCTION

The term "serodiscordant couples" refers to an intimate partnership in which one partner is human immunodeficiency virus (HIV) positive and the other HIV negative. They form a special population which are constantly at risk of acquiring infection, require safer sexual and reproductive options, and are in constant psychological and emotional distress.

AIMS

To describe the social, sexual, and reproductive issues and their impact on serodiscordant couples.

MATERIALS AND METHODS

A cross-sectional study was conducted on HIV-serodiscordant couples, admitted or attending our outpatient department, where the couples had not separated. A detailed interview of the partners on social, sexual, and reproductive issues was conducted and the data were endorsed in the pro forma.

RESULTS

Sixty-four serodiscordant couples were included in the study. Sixty-two (96.8%) males were seropositive compared to 2 (3.1%) females. Sixty-one (95.3%) patients were married and 3 (4.6%) were unmarried. Thirty-six (56.2%) patients were between the age group of 21 and 35 years, 21 (32.8%) between 36 and 55 years, and 7 (10.9%) between 56 and 70 years. Sixty-two (96.8%) patients had a heterosexual orientation compared to 2 (3.1%) patients who were homosexual. Twenty-one (32.8%) patients had a history of sexual encounter outside the relation while 27 (42.1%) were not aware of the source of infection. Fifty-one (79.6%) patients were on antiretroviral therapy (ART) compared to 13 (20.3%) patients who were not on ART. Thirty-one (48.4%) patients admitted to have a constant strain in relation while 16 (25%) were practicing safe sex. Thirty-nine (60.9%) patients had fear of disease transmission while 26 (40.6%) had fear of pregnancy. Forty-nine (76.5%) patients had children at the time of detection while 15 (23.4%) had no issue. Forty-one (64%) patients expressed desire to have children as compared to 23 (35.9%).

CONCLUSION

The unique requirements of serodiscordant couples in terms of providing them safer sexual and reproductive options to prevent the transmission of HIV to the seronegative partner or the child during pregnancy need to be addressed for better patient management.

摘要

引言

“血清学不一致的伴侣”一词指的是一种亲密关系,其中一方为人类免疫缺陷病毒(HIV)阳性,另一方为HIV阴性。他们构成了一个特殊群体,持续面临感染风险,需要更安全的性和生殖选择,并且长期处于心理和情感困扰之中。

目的

描述血清学不一致伴侣的社会、性和生殖问题及其对他们的影响。

材料与方法

对入住或就诊于我们门诊部且未分居的HIV血清学不一致伴侣进行了一项横断面研究。对伴侣双方就社会、性和生殖问题进行了详细访谈,并将数据填入表格。

结果

64对血清学不一致伴侣纳入了研究。62名(96.8%)男性血清学呈阳性,2名(3.1%)女性血清学呈阳性。61名(95.3%)患者已婚,3名(4.6%)未婚。36名(56.2%)患者年龄在21至35岁之间,21名(32.8%)在36至55岁之间,7名(10.9%)在56至70岁之间。62名(96.8%)患者为异性恋,2名(3.1%)患者为同性恋。21名(32.8%)患者有婚外性接触史,27名(42.1%)患者不知道感染源。51名(79.6%)患者正在接受抗逆转录病毒治疗(ART),13名(20.3%)患者未接受ART。31名(48.4%)患者承认关系中存在持续压力,16名(25%)患者采取安全性行为。39名(60.9%)患者担心疾病传播,26名(40.6%)患者担心怀孕。49名(76.5%)患者在检测时已有子女,15名(23.4%)没有子女。41名(64%)患者表示希望生育,23名(35.9%)则不然。

结论

为了更好地管理患者,需要满足血清学不一致伴侣在提供更安全性和生殖选择方面的独特需求,以防止HIV在怀孕期间传播给血清学阴性的伴侣或孩子。