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肠道病毒D68:一种具有临床重要性的呼吸道肠道病毒。

Enterovirus D68: a clinically important respiratory enterovirus.

作者信息

Foster Charles B, Friedman Neil, Carl John, Piedimonte Giovanni

机构信息

Center for Pediatric Infectious Diseases, Pediatric Institute, and Children's Hospital, Cleveland Clinic; Associate Professor of Pediatrics, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.

Director, Center for Pediatric Neurology, Pediatric Institute, and Children's Hospital, Cleveland Clinic.

出版信息

Cleve Clin J Med. 2015 Jan;82(1):26-31. doi: 10.3949/ccjm.82a.14166.

Abstract

Seasonal peaks of viral respiratory illnesses are common during late summer and early fall and have often been attributed to human rhinovirus. In the fall of 2014, the number of children hospitalized with severe lower respiratory symptoms and asthma suddenly increased, and the children tested positive by sequencing for enterovirus D68 (EV-D68). As the outbreak unfolded, a possible association was also observed between EV-D68 infection, polio-like acute flaccid paralysis, and cranial neuropathy in children.

摘要

病毒性呼吸道疾病的季节性高峰在夏末和初秋很常见,通常被认为是由人鼻病毒引起的。2014年秋季,因严重下呼吸道症状和哮喘住院的儿童数量突然增加,通过测序检测这些儿童肠道病毒D68(EV-D68)呈阳性。随着疫情的发展,还观察到儿童EV-D68感染、类脊髓灰质炎急性弛缓性麻痹和颅神经病变之间可能存在关联。

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