Bergin D J, Lapins N A, Deffer T A
Department of Surgery, Letterman Army Medical Center, Presidio of San Francisco, California 94129-6700.
Ophthalmic Plast Reconstr Surg. 1986;2(4):201-4. doi: 10.1097/00002341-198601070-00005.
Keratoacanthoma of the lower eyelid developed in two patients. In the first case, conventional excision biopsy necessitated a large eyelid reconstruction procedure. In the second case, 5-fluorouracil was injected into the base of the keratoacanthoma. Both treatments resulted in complete resolution of the lesion with excellent cosmesis. Thus, intralesional 5-fluorouracil can be useful for keratoacanthomas of the eyelid in patients who are not good candidates for surgery.