吸烟对脉络膜厚度、中心黄斑血管和视盘灌注的影响。

The effect of the smoking on choroidal thickness, central macular vascular and optic disc perfusion.

机构信息

Izmir Katip Celebi University Hospital, Turkey.

出版信息

Photodiagnosis Photodyn Ther. 2019 Dec;28:142-145. doi: 10.1016/j.pdpdt.2019.09.005. Epub 2019 Sep 20.

DOI:10.1016/j.pdpdt.2019.09.005

PMID:31546044

Abstract

OBJECTIVES

To compare choroidal thickness, central macular vascular perfusion and optic disc perfusion in smokers and non-smokers.

METHODS

Smoker participants defined group I and non-smoker participants(group II) Optical coherence tomography angiography (OCTA) performed to all volunteers and choroidal thickness, central macular vascular and optic disc perfusion were measured.

RESULTS

In group I, 30 eyes of the 30 participants (6 male and 24 female) evaluated and in group II, 32 eyes of the 32 participants (13 male and 19 female) evaluated. The mean age of the volunteers were 43.09 ± 14.28 and 42.2 ± 8.24 year-old in group I and group II, respectively. The mean choroidal thickness were 345 ± 74 μm and 301.6 ± 71 μm in group I and group II, respectively (p = 0.022). The mean optic disc perfusions were 45.17 ± 1.46% and 45.25 ± 1.43% in group I and group II, respectively (p = 0.82). The mean central macular vascular perfusions were 20.20 ± 7.17% and 18.65 ± 7.46% in group I and group II, respectively (p = 0.4). There are a negative correlation between macular vascular perfusion, optic disc perfusion and smoking period (p = 0.32 and 0.62, respectively.) CONCLUSION: Our study revealed that smoking statistically significantly effected choroidal thickness but effected central macular vascular and optic disc perfusion changes were not statistically significant.

摘要

目的

比较吸烟者和非吸烟者的脉络膜厚度、黄斑中心区血管血流灌注和视盘血流灌注。

方法

将吸烟者定义为组 I，非吸烟者定义为组 II，对所有志愿者进行光学相干断层扫描血管造影（OCTA）检查，测量脉络膜厚度、黄斑中心区血管血流和视盘血流灌注。

结果

在组 I 中，评估了 30 名参与者的 30 只眼（6 名男性和 24 名女性），在组 II 中，评估了 32 名参与者的 32 只眼（13 名男性和 19 名女性）。志愿者的平均年龄分别为组 I 中的 43.09±14.28 岁和组 II 中的 42.2±8.24 岁。组 I 和组 II 的平均脉络膜厚度分别为 345±74μm 和 301.6±71μm（p=0.022）。组 I 和组 II 的平均视盘血流灌注分别为 45.17±1.46%和 45.25±1.43%（p=0.82）。组 I 和组 II 的平均黄斑中心区血管血流灌注分别为 20.20±7.17%和 18.65±7.46%（p=0.4）。黄斑血管灌注、视盘血流灌注与吸烟时间呈负相关（p=0.32 和 0.62）。