内异症患者生育力保存的作用：系统评价。
The Role of Fertility Preservation in Women with Endometriosis: A Systematic Review.
机构信息
Department of Obstetrics, Gynecology and Fertility, Lis Maternity Hospital (Drs. Lantsberg and Cohen); Sourasky Tel-Aviv Medical Center (Drs. Lantsberg and Cohen), and Sackler Faculty of Medicine (Drs. Lantsberg and Cohen), Tel-Aviv University, Israel.
Department of Obstetrics and Gynecology, Monash University, Clayton (Prof. Rombauts and Dr. Fernando), Australia; Women's Health, Monash Health, Clayton (Prof. Rombauts and Dr. Fernando), Australia.
出版信息
J Minim Invasive Gynecol. 2020 Feb;27(2):362-372. doi: 10.1016/j.jmig.2019.09.780. Epub 2019 Sep 20.
OBJECTIVE
To summarize the available evidence concerning fertility preservation techniques in the context of women with endometriosis.
DATA SOURCES
We searched for studies published between 1984 and 2019 on endometriosis and Assisted Reproductive Technology outcomes. We searched MEDLINE and PubMed and performed a manual search of reference lists within identified studies.
METHODS OF STUDY SELECTION
A total of 426 articles were identified, and 7 studies were eligible to be included for the systematic review. We included all published studies, excluding reviews, case reports, and animal studies.
TABULATION, INTEGRATION, AND RESULTS: Despite a significant increase in the number of studies addressing fertility preservation over the study period, we found a relative lack of evidence addressing the use of fertility preservation techniques in women with endometriosis. The studies identified included 2 case reports, 1 histological science study, and 4 retrospective cohort studies.
CONCLUSION
Women with endometriosis may benefit from fertility preservation techniques. However, there currently is a paucity of data in this population, especially when compared with other indications for fertility preservation. Although much knowledge can be translated from the oncofertility discipline, we have identified and discussed endometriosis-related changes to ovarian reserve and oocyte health that justify further well-designed research to confirm that fertility preservation outcomes are similar for women with endometriosis.
目的
总结有关子宫内膜异位症女性生育力保存技术的现有证据。
资料来源
我们检索了 1984 年至 2019 年间发表的关于子宫内膜异位症和辅助生殖技术结局的研究。我们检索了 MEDLINE 和 PubMed，并对已确定研究的参考文献进行了手动检索。
研究选择方法
共确定了 426 篇文章，有 7 项研究符合系统评价的纳入标准。我们纳入了所有已发表的研究，排除了综述、病例报告和动物研究。
列表、综合和结果：尽管在研究期间，涉及生育力保存的研究数量显著增加，但我们发现，针对子宫内膜异位症女性使用生育力保存技术的证据相对较少。确定的研究包括 2 例病例报告、1 项组织学科学研究和 4 项回顾性队列研究。
结论
子宫内膜异位症女性可能受益于生育力保存技术。然而，目前在该人群中数据匮乏，尤其是与其他生育力保存适应症相比。尽管许多知识可以从肿瘤生育力领域转化，但我们已经确定并讨论了与卵巢储备和卵母细胞健康相关的子宫内膜异位症变化，这些变化需要进一步精心设计的研究来证实，对于患有子宫内膜异位症的女性，生育力保存的结果是相似的。
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