Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Guangdong Province, China.
Department of Ophthalmology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu Province, China.
Indian J Ophthalmol. 2019 Oct;67(10):1629-1633. doi: 10.4103/ijo.IJO_250_19.
This study evaluated bimanual intracapsular irrigation-aspiration for ectopia lentis with use of a small incision for 4-point scleral fixation of a foldable posterior-chamber intraocular lens (IOL) and anterior vitrectomy in patients with Marfan syndrome.
We performed a retrospective study of 18 eyes from 10 patients with Marfan syndrome who underwent surgical intervention for ectopia lentis at our clinic between July 2012 and September 2018. In this study, intraoperative and postoperative complications, uncorrected visual acuity, best-corrected visual acuity, spherical equivalent, intraocular pressure, and endothelial cell density were evaluated.
No intraoperative complications were reported. In all cases, early postoperative evaluation revealed a clear cornea, round pupil, and well-centered IOL. Mean logMAR uncorrected visual acuity improved from 1.09 preoperatively to 0.56 postoperatively (P < 0.05). Mean logMAR best-corrected visual acuity improved from 0.45 preoperatively to 0.17 postoperatively (P < 0.05). Aside from transient ocular hypertension, no postoperative complications were reported.
The combined surgical technique presented above yields excellent visual outcomes with an extremely low incidence of complications. This approach is simple, safe, and effective in the treatment of ectopia lentis in patients with Marfan syndrome.
本研究评估了在马凡综合征患者中,通过小切口四点巩膜固定可折叠后房型人工晶状体(IOL)和前段玻璃体切除术,对晶状体异位进行双手囊内灌洗抽吸的效果。
我们对 2012 年 7 月至 2018 年 9 月在我科接受晶状体异位手术治疗的 10 例马凡综合征患者的 18 只眼进行了回顾性研究。本研究评估了术中及术后并发症、未矫正视力、最佳矫正视力、等效球镜、眼压和内皮细胞密度。
未报告术中并发症。所有病例术后早期评估均显示角膜透明、瞳孔圆、IOL 居中良好。平均 logMAR 未矫正视力从术前的 1.09 提高到术后的 0.56(P<0.05)。平均 logMAR 最佳矫正视力从术前的 0.45 提高到术后的 0.17(P<0.05)。除一过性高眼压外,无其他术后并发症。
上述联合手术技术具有极佳的视觉效果,且并发症发生率极低。该方法在治疗马凡综合征患者的晶状体异位方面简单、安全且有效。