Smith B R, Beyer-Machule C K, Cheng H M, Pitts W C
Department of Opthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston.
Ophthalmic Plast Reconstr Surg. 1988;4(4):193-201. doi: 10.1097/00002341-198804040-00001.
A year-long study was undertaken to serially evaluate the tissue changes occurring in dermis-fat graft (DFG) after orbital implantation in nine guinea pigs. Methods used to evaluate the DFGs were histology, magnetic resonance imaging, morphometric analysis, and clinical observations. The histology of a 1-year-old failed human dermis-fat graft has been included for completeness. The study reveals that clinically successful DFGs have a fibrous capsule surrounding the DFG. Minimal revascularization was present. The grafts appear to undergo continual histological changes for approximately 9 months before a steady-state condition ensues. Of interest are changes in the deep-orbital fat posterior to the DFG.
对9只豚鼠眼眶植入真皮脂肪移植体（DFG）后发生的组织变化进行了为期一年的系列评估。用于评估DFG的方法包括组织学、磁共振成像、形态计量分析和临床观察。为全面起见，纳入了1例1岁失败的人真皮脂肪移植体的组织学情况。研究表明，临床上成功的DFG有一层纤维包膜包裹。血管再生极少。移植体在达到稳定状态之前，似乎会持续发生约9个月的组织学变化。DFG后方眼眶深部脂肪的变化值得关注。
