Richardson R R, Siqueira E B, Cerullo L J
Neurosurgery. 1979 Sep;5(3):344-8.
Spinal epidural neurostimulation, which evolved from dorsal column stimulation, has been found to be effective in the treatment of acute and chronic intractable pain. Urban and Hashold have shown that it is a safe, simplified alternative to dorsal column stimulation, especially because laminectomy is not required if the electrodes are inserted percutaneously. Percutaneous epidural neurostimulation is also advantageous because there can be a diagnostic trial period before permanent internalization and implantation. This diagnostic and therapeutic modality has been used in 36 patients during the past 3 years at Northwestern Memorial Hospital. Eleven of these patients had acute intractable pain, which was defined as pain of less than 1 year in duration. Initial postimplantation results from the 36 patients indicate that spinal epidural neurostimulation is most effective in treating the intractable pain of diabetes, arachnoiditis, and post-traumatic and postamputation neuroma. Long term follow-up, varying from 1 year to 3 years postimplantation in the 20 initially responding patients, indicates that the neurostimulation continues to provide significant pain relief (50% or greater) in a majority of the patients who experienced initial significant pain relief.
脊髓硬膜外神经刺激起源于脊髓后柱刺激,已被证明对治疗急慢性顽固性疼痛有效。厄本和哈肖尔德指出,它是脊髓后柱刺激的一种安全、简化的替代方法,特别是如果经皮插入电极,则无需进行椎板切除术。经皮硬膜外神经刺激也具有优势,因为在永久植入体内之前可以有一个诊断试验期。在过去三年中,西北纪念医院对36名患者使用了这种诊断和治疗方式。其中11名患者患有急性顽固性疼痛,定义为病程少于1年的疼痛。这36名患者植入后的初步结果表明,脊髓硬膜外神经刺激在治疗糖尿病性顽固性疼痛、蛛网膜炎以及创伤后和截肢后神经瘤方面最有效。对最初有反应的20名患者进行了1至3年的长期随访,结果表明,在大多数最初疼痛得到显著缓解的患者中,神经刺激继续提供显著的疼痛缓解(50%或更高)。