• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在终末期骨关节炎全膝关节置换术的结果中,软骨钙质沉着症患者的术后疼痛、功能和并发症无差异。

There is no difference in postoperative pain, function and complications in patients with chondrocalcinosis in the outcome of total knee arthroplasty for end-stage osteoarthritis.

机构信息

Department of Orthopaedic Surgery, Spaarne Gasthuis, Spaarnepoort 1, 2130AT, Hoofddorp, The Netherlands.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2020 Sep;28(9):2970-2979. doi: 10.1007/s00167-019-05725-7. Epub 2019 Sep 24.

DOI:10.1007/s00167-019-05725-7
PMID:31552473
Abstract

PURPOSE

Chondrocalcinosis is the radiographic appearance of calcium crystals in cartilage and other soft tissue. It is suggested that preoperative chondrocalcinosis predicts a worse outcome after total knee arthroplasty and it is unclear if chondrocalcinosis leads to more postoperative complications. This study aimed to compare function, pain, postoperative complications, postoperative signs of acute arthritis and revision rates between patients with and without chondrocalcinosis undergoing total knee arthroplasty for osteoarthritis.

METHODS

In this retrospective cohort study performed in 2017, 408 knees in 392 patients (16 bilateral total knee arthroplasties) were included. None of the patients received additional synovectomy. PROMs were evaluated after 1 year (n = 294) and 5 years (n = 308). The follow-up for clinical data was 5 years (n = 408). The range of final follow-up was 57-84 months. All preoperative radiographs were scored for chondrocalcinosis and Oxford Knee Score, Knee Society Score and Algofunctional Index were used to assess outcome. All clinical records were screened for postoperative complications (excessive wound discharge, infection, loosening, PAO, stiffness), arthritis after surgery and reoperation or revision for any reason.

RESULTS

Sixty-three knees (15.4%) showed signs of chondrocalcinosis. Male gender, higher age and lower BMI were risk factors for chondrocalcinosis. No difference was found in Oxford Knee Score, Knee Society Score and Algofunctional Index, nor in postoperative complications, postoperative signs of acute arthritis and revision rate.

CONCLUSION

Patients with and without chondrocalcinosis have the same outcome after total knee arthroplasty related to pain, functionality, complications, arthritis and revision after surgery for end-stage osteoarthritis. Chondrocalcinosis is not a contraindication for total knee arthroplasty and additional synovectomy is unnecessary.

LEVEL OF EVIDENCE

III.

摘要

目的

软骨钙质沉着症是指软骨和其他软组织中钙晶体的放射影像学表现。有研究表明,术前软骨钙质沉着症预示着全膝关节置换术后的结果更差,并且尚不清楚软骨钙质沉着症是否会导致更多的术后并发症。本研究旨在比较患有和不患有软骨钙质沉着症的骨关节炎患者行全膝关节置换术后的功能、疼痛、术后并发症、术后急性关节炎表现和翻修率。

方法

在 2017 年进行的这项回顾性队列研究中,纳入了 392 名患者(16 例双侧全膝关节置换术)的 408 膝。所有患者均未接受额外的滑膜切除术。在术后 1 年(n=294)和 5 年(n=308)时评估了 PROMs。临床数据的随访时间为 5 年(n=408)。最终随访时间范围为 57-84 个月。所有术前的 X 线片均进行软骨钙质沉着症评分,并采用牛津膝关节评分(Oxford Knee Score,OKS)、膝关节协会评分(Knee Society Score,KSS)和 Algofunctional 指数(Algofunctional Index,AIF)评估结局。所有临床记录均筛查了术后并发症(过度伤口渗出、感染、松动、PAO、僵硬)、术后关节炎以及任何原因的再次手术或翻修。

结果

63 膝(15.4%)存在软骨钙质沉着症的迹象。男性、较高的年龄和较低的 BMI 是软骨钙质沉着症的危险因素。在 OKS、KSS 和 AIF 评分、术后并发症、术后急性关节炎表现和翻修率方面,两组之间无差异。

结论

在与疼痛、功能、并发症、关节炎和术后翻修相关的终末期骨关节炎行全膝关节置换术后,有和没有软骨钙质沉着症的患者结局相同。软骨钙质沉着症不是全膝关节置换术的禁忌证,也不需要额外的滑膜切除术。

证据等级

III 级。

相似文献

1
There is no difference in postoperative pain, function and complications in patients with chondrocalcinosis in the outcome of total knee arthroplasty for end-stage osteoarthritis.在终末期骨关节炎全膝关节置换术的结果中,软骨钙质沉着症患者的术后疼痛、功能和并发症无差异。
Knee Surg Sports Traumatol Arthrosc. 2020 Sep;28(9):2970-2979. doi: 10.1007/s00167-019-05725-7. Epub 2019 Sep 24.
2
Does primary or secondary chondrocalcinosis influence long-term survivorship of unicompartmental arthroplasty?原发性或继发性软骨钙质沉着症是否影响单髁关节置换术的长期存活率?
Clin Orthop Relat Res. 2012 Jul;470(7):1973-9. doi: 10.1007/s11999-011-2211-5. Epub 2011 Dec 13.
3
Does chondrocalcinosis affect Knee Society scores and range of motion after TKA?软骨钙质沉着症是否会影响 TKA 后膝关节评分和关节活动范围?
Clin Orthop Relat Res. 2014 May;472(5):1512-7. doi: 10.1007/s11999-013-3447-z. Epub 2014 Jan 3.
4
Lateral meniscus with tears or with histologic calcification does not increase the risk of lateral osteoarthritis after medial unicompartmental arthroplasty.外侧半月板撕裂或组织学钙化并不会增加内侧单髁关节置换术后外侧骨关节炎的风险。
Int Orthop. 2023 Oct;47(10):2477-2485. doi: 10.1007/s00264-023-05907-6. Epub 2023 Jul 28.
5
Comparison of outcomes after UKA in patients with and without chondrocalcinosis: a matched cohort study.有和没有假性痛风的患者行单髁置换术后的疗效比较:一项配对队列研究。
Knee Surg Sports Traumatol Arthrosc. 2017 Jan;25(1):319-324. doi: 10.1007/s00167-015-3578-8. Epub 2015 Mar 19.
6
Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review.软骨钙质沉着症不会影响全膝关节或单髁膝关节置换术后患者的功能结果和假体存活率:系统评价。
Knee Surg Sports Traumatol Arthrosc. 2022 Mar;30(3):1039-1049. doi: 10.1007/s00167-021-06519-6. Epub 2021 Mar 6.
7
Unicompartmental Knee Arthroplasty vs Total Knee Arthroplasty for Medial Compartment Arthritis in Patients Older Than 75 Years: Comparable Reoperation, Revision, and Complication Rates.75岁以上患者内侧间室关节炎的单髁膝关节置换术与全膝关节置换术:再手术、翻修及并发症发生率相当
J Arthroplasty. 2017 Jun;32(6):1792-1797. doi: 10.1016/j.arth.2017.01.020. Epub 2017 Jan 24.
8
Similar postoperative patient-reported outcome in both second generation patellofemoral arthroplasty and total knee arthroplasty for treatment of isolated patellofemoral osteoarthritis: a systematic review.髌股关节骨关节炎患者接受第二代髌股关节置换术与全膝关节置换术治疗的术后患者报告结局相似:一项系统评价。
Knee Surg Sports Traumatol Arthrosc. 2019 Jul;27(7):2226-2237. doi: 10.1007/s00167-018-5151-8. Epub 2018 Sep 28.
9
Revision total knee arthroplasty for failed high tibial osteotomy and unicompartmental knee arthroplasty have similar patient-reported outcome measures in a two-year follow-up study.在一项为期两年的随访研究中,针对失败的高位胫骨截骨术和单髁膝关节置换术进行的全膝关节翻修术,患者报告的结局指标相似。
Bone Joint J. 2017 Oct;99-B(10):1329-1334. doi: 10.1302/0301-620X.99B10.BJJ-2017-0034.R1.
10
Arthritic progression secondary to meniscus root tear treated with knee arthroplasty demonstrates similar outcomes to primary osteoarthritis: a matched case-control comparison.半月板根撕裂继发骨关节炎行膝关节置换术后的进展与原发性骨关节炎的结果相似:一项匹配的病例对照比较。
Knee Surg Sports Traumatol Arthrosc. 2021 Jun;29(6):1977-1982. doi: 10.1007/s00167-020-06273-1. Epub 2020 Sep 25.

引用本文的文献

1
Effects of celecoxib combined with glucosamine hydrochloride in the management of knee osteoarthritis.塞来昔布联合盐酸氨基葡萄糖治疗膝骨关节炎的效果
Am J Transl Res. 2025 Aug 15;17(8):6359-6369. doi: 10.62347/AHTO9889. eCollection 2025.
2
Correlation of revision rate of unicompartmental knee arthroplasty with total knee arthroplasty: a meta-analysis of clinical studies and worldwide arthroplasty registers.单髁膝关节置换术翻修率与全膝关节置换术翻修率的相关性:临床研究和全球关节置换登记处的荟萃分析。
Arch Orthop Trauma Surg. 2024 Nov;144(11):4873-4886. doi: 10.1007/s00402-024-05574-1. Epub 2024 Oct 15.
3
Radiographically detectable intra-articular mineralization: Predictor of knee osteoarthritis outcomes or only an indicator of aging? A brief report from the osteoarthritis initiative.
影像学可检测到的关节内矿化:膝关节骨关节炎预后的预测指标还是仅仅是衰老的一个指标?骨关节炎倡议的简要报告
Osteoarthr Cartil Open. 2023 Feb 23;5(2):100348. doi: 10.1016/j.ocarto.2023.100348. eCollection 2023 Jun.
4
Outcomes and resource utilization in calcium pyrophosphate deposition disease patients who underwent total knee arthroplasty: a cross-sectional analysis.焦磷酸钙沉积病患者行全膝关节置换术后的结局和资源利用:一项横断面分析。
Clin Rheumatol. 2022 Jun;41(6):1817-1824. doi: 10.1007/s10067-022-06101-6. Epub 2022 Feb 17.
5
Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review.软骨钙质沉着症不会影响全膝关节或单髁膝关节置换术后患者的功能结果和假体存活率:系统评价。
Knee Surg Sports Traumatol Arthrosc. 2022 Mar;30(3):1039-1049. doi: 10.1007/s00167-021-06519-6. Epub 2021 Mar 6.
6
Outcome domains reported in calcium pyrophosphate deposition studies: A scoping review by the OMERACT CPPD working group.焦磷酸钙沉积研究中报告的结局领域:OMERACT CPPD 工作组的范围综述。
Semin Arthritis Rheum. 2020 Aug;50(4):719-727. doi: 10.1016/j.semarthrit.2020.05.015. Epub 2020 May 30.