Department of Antibiotic Resistance and Infection Prevention, Norwegian Institute of Public Health, Oslo, Norway.
Department of Tuberculosis, Blood Borne and Sexually Transmitted Infections, Norwegian Institute of Public Health, Oslo, Norway.
Euro Surveill. 2019 Sep;24(38). doi: 10.2807/1560-7917.ES.2019.24.38.1800676.
IntroductionIn 2015, there was an increase in the number of asylum seekers arriving in Europe. Like in other countries, deciding screening priorities for tuberculosis (TB) and meticillin-resistant (MRSA) was a challenge. At least five of 428 municipalities chose to screen asylum seekers for MRSA before TB; the Norwegian Institute for Public Health advised against this.AimTo evaluate the MRSA/TB screening results from 2014 to 2016 and create a generalised framework for screening prioritisation in Norway through simulation modelling.MethodsThis is a register-based cohort study of asylum seekers using data from the Norwegian Surveillance System for Communicable Diseases from 2014 to 2016. We used survey data from municipalities that screened all asylum seekers for MRSA and denominator data from the Directorate of Immigration. A comparative risk assessment model was built to investigate the outcomes of prioritising between TB and MRSA in screening regimes.ResultsOf 46,090 asylum seekers, 137 (0.30%) were diagnosed with active TB (notification rate: 300/100,000 person-years). In the municipalities that screened all asylum seekers for MRSA, 13 of 1,768 (0.74%) were found to be infected with MRSA. The model estimated that screening for MRSA would prevent eight MRSA infections while prioritising TB screening would prevent 24 cases of active TB and one death.ConclusionOur findings support the decision to advise against screening for MRSA before TB among newly arrived asylum seekers. The model was an effective tool for comparing screening priorities and can be applied to other scenarios in other countries.
简介
2015 年,抵达欧洲的寻求庇护者人数有所增加。与其他国家一样,确定结核病(TB)和耐甲氧西林金黄色葡萄球菌(MRSA)的筛查优先级是一项挑战。在 428 个城市中,至少有五个城市选择在筛查 TB 之前对 MRSA 进行筛查;挪威公共卫生研究所建议不要这样做。
目的
通过模拟建模,评估 2014 年至 2016 年的 MRSA/TB 筛查结果,并为挪威的筛查优先级制定通用框架。
方法
这是一项基于登记的寻求庇护者队列研究,使用了 2014 年至 2016 年挪威传染病监测系统的数据。我们使用对所有寻求庇护者进行 MRSA 筛查的城市的调查数据和移民局的分母数据。建立了一个比较风险评估模型,以调查在筛查方案中优先考虑 TB 和 MRSA 的结果。
结果
在 46090 名寻求庇护者中,有 137 人(0.30%)被诊断患有活动性结核病(通报率:300/100000 人年)。在对所有寻求庇护者进行 MRSA 筛查的城市中,发现 13 名/1768 名(0.74%)感染了 MRSA。该模型估计,筛查 MRSA 将预防 8 例 MRSA 感染,而优先筛查 TB 将预防 24 例活动性结核病和 1 例死亡。
结论
我们的研究结果支持不建议在新抵达的寻求庇护者中筛查 MRSA 之前筛查 TB 的决定。该模型是比较筛查优先级的有效工具,可应用于其他国家的其他情况。