2015 - 2016年哥伦比亚巴兰基亚疫情爆发前献血者中寨卡病毒的血清流行率。

Seroprevalence of Zika virus among blood donors before the epidemic in Barranquilla, Colombia, 2015-2016.

作者信息

Bayona-Pacheco Brayan, Acosta-Reyes Jorge, Navarro Edgar, San-Juan Homero, Bula Johan, Baquero Hernando

机构信息

Departamento de Medicina, División Ciencias de la Salud, Universidad del Norte, Km 5, vía Puerto Colombia, Área Metropolitana de Barranquilla, Colombia.

Departamento de Salud Pública, División Ciencias de la Salud, Universidad del Norte, Km 5, vía Puerto Colombia, Área Metropolitana de Barranquilla, Colombia.

出版信息

An Acad Bras Cienc. 2019 Sep 23;91(3):e20180860. doi: 10.1590/0001-3765201920180860. eCollection 2019.

DOI:10.1590/0001-3765201920180860

PMID:31553367

Abstract

The first cases of Zika virus infection in Colombia were reported and confirmed in October 2015. The objective of the study was estimate the seroprevalence of ZIKV infection during the pre-epidemic phase in Barranquilla, Colombia, and demonstrate the presence of virus before the Colombian Ministry of Health confirmed the first case. We conducted a descriptive study of the seroprevalence of Zika virus in 390 samples obtained from a blood bank located in Barranquilla, Colombia - a city endemic for dengue, and with a recent history of a Chikungunya disease epidemic. The serum pools were tested using Euroimmun ZIKV ELISA kit. Seroprevalence of Zika virus IgG were: May 2015: 0%, June and July 2015: 2.62% (95% CI = 0.28-12.13) and August 2015: 5.35% (95% CI = 1.74-16.74). This brings to our attention the need for extending the surveillance period of this virus in order to adequately assess its teratogenic effects.

摘要

2015年10月，哥伦比亚报告并确认了首批寨卡病毒感染病例。本研究的目的是估计在哥伦比亚巴兰基亚流行前期寨卡病毒感染的血清阳性率，并在哥伦比亚卫生部确认首例病例之前证明病毒的存在。我们对从哥伦比亚巴兰基亚一家血库采集的390份样本进行了寨卡病毒血清阳性率的描述性研究，巴兰基亚是登革热的地方性流行城市，近期有基孔肯雅热疾病流行史。血清样本采用欧蒙寨卡病毒ELISA试剂盒进行检测。寨卡病毒IgG的血清阳性率分别为：2015年5月：0%；2015年6月和7月：2.62%（95%置信区间=0.28-12.13）；2015年8月：5.35%（95%置信区间=1.74-16.74）。这使我们注意到有必要延长对该病毒的监测期，以便充分评估其致畸作用。