Sallmon Hannes, Moledina Shahin, Albert Dimpna C, Beghetti Maurice, Berger Rolf M F, Bonnet Damien, Bukova Mila, Koestenberger Martin, Meinel Katharina, Reinhardt Zdenka, Tulloh Robert M R, de Wolf Daniel, Hansmann Georg
Department of Pediatric Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Department of Paediatric Cardiology, Great Ormond Street Hospital NHS Foundation Trust, London, UK.
Cardiol Young. 2019 Nov;29(11):1323-1327. doi: 10.1017/S104795111900235X. Epub 2019 Sep 26.
Pulmonary hypertension is a complex and progressive condition that is either idiopathic or heritable, or associated with one or multiple health conditions, with or without congenital or acquired cardiovascular disease. Recent developments have tremendously increased the armamentarium of diagnostic and therapeutic approaches in children and young adults with pulmonary hypertension that is still associated with a high morbidity and mortality. These modalities include non-invasive imaging, pharmacotherapy, interventional and surgical procedures, and supportive measures. The optimal, tailored diagnostic and therapeutic strategies for pulmonary hypertension in the young are rapidly evolving but still face enormous challenges: Healthcare providers need to take the patient's age, development, disease state, and family concerns into account when initiating advanced diagnostics and treatment. Therefore, there is a need for guidance on core and advanced medical training in paediatric pulmonary hypertension. The Association for European Paediatric and Congenital Cardiology working group "pulmonary hypertension, heart failure and transplantation" has produced this document as an expert consensus statement; however, all recommendations must be considered and applied in the context of the local and national infrastructure and legal regulations.
肺动脉高压是一种复杂的进行性疾病,可为特发性或遗传性,或与一种或多种健康状况相关,伴或不伴有先天性或后天性心血管疾病。最近的进展极大地增加了患有肺动脉高压的儿童和年轻人的诊断和治疗方法储备,而该病仍具有较高的发病率和死亡率。这些方法包括非侵入性成像、药物治疗、介入和外科手术以及支持措施。针对年轻人肺动脉高压的最佳、量身定制的诊断和治疗策略正在迅速发展,但仍面临巨大挑战:医疗保健提供者在启动高级诊断和治疗时需要考虑患者的年龄、发育情况、疾病状态和家庭关切。因此,需要有关儿科肺动脉高压核心和高级医学培训的指导。欧洲儿科和先天性心脏病学协会“肺动脉高压、心力衰竭和移植”工作组编写了本文件作为专家共识声明;然而,所有建议都必须在当地和国家基础设施及法律法规的背景下加以考虑和应用。