急性视网膜坏死的超广角眼底成像：临床特征和视觉意义。
Ultra-wide-field fundus imaging of acute retinal necrosis: clinical characteristics and visual significance.
机构信息
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China.
出版信息
Eye (Lond). 2020 May;34(5):864-872. doi: 10.1038/s41433-019-0587-8. Epub 2019 Sep 25.
OBJECTIVES
To investigate the clinical characteristics of acute retinal necrosis (ARN) with ultra-wide-field imaging (UWFI) and analyse their visual significance.
METHODS
Clinical and UWFI records of patients diagnosed with ARN at a single centre over 2 years were reviewed.
RESULTS
In 38 eyes of 35 patients, the clinical manifestations of ARN on UWFI included patchy (12 eyes) or fan-shaped necrotic lesions (26 eyes), retinal arterial obliteration (38 eyes), vitritis (38 eyes), retinal venous haemorrhage (19 eyes), and vitreous haemorrhage (6 eyes). Retinal detachment was associated with the number of retinal quadrants involved (β = 2.145, P = 0.005). LogMAR BCVA at last follow-up was associated with logMAR BCVA at presentation (β = 0.473, P = 0.004) and retinal detachment (β = 0.367, P = 0.020).
CONCLUSION
UWFI is useful for detecting retinal lesions in ARN, especially peripheral lesions or through opaque media, and provides valuable information concerning visual prognosis.
目的
通过超广角成像（UWFI）研究急性视网膜坏死（ARN）的临床特征，并分析其视觉意义。
方法
回顾 2 年内单中心诊断为 ARN 的患者的临床和 UWFI 记录。
结果
在 35 名患者的 38 只眼中，ARN 的 UWFI 表现包括斑片状（12 只眼）或扇形坏死病变（26 只眼）、视网膜动脉闭塞（38 只眼）、虹膜炎（38 只眼）、视网膜静脉出血（19 只眼）和玻璃体积血（6 只眼）。视网膜脱离与受累视网膜象限数量相关（β=2.145，P=0.005）。末次随访时的 logMAR BCVA 与就诊时的 logMAR BCVA（β=0.473，P=0.004）和视网膜脱离（β=0.367，P=0.020）相关。
结论
UWFI 有助于检测 ARN 的视网膜病变，尤其是周边病变或通过不透明介质，提供有价值的视觉预后信息。
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