2型糖尿病患者血清钙水平与腰围及其他生化健康预测指标的关联

Association of Serum Calcium Level with Waist Circumference and Other Biochemical Health-care Predictors among Patients with Type 2 Diabetes.

作者信息

Shahwan Moyad J, Khattab Mohammed H, Jairoun Ammar A

机构信息

Department of Clinical Sciences, College of Pharmacy, Ajman University, Ajman, United Arab Emirates.

Consumer Product Safety Section, Public Health and Safety Department, Dubai Municipality, Dubai, United Arab Emirates.

出版信息

J Pharm Bioallied Sci. 2019 Jul-Sep;11(3):292-298. doi: 10.4103/jpbs.JPBS_137_19.

DOI:10.4103/jpbs.JPBS_137_19

PMID:31555037

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6662041/

Abstract

INTRODUCTION

This study aimed to find the association of serum calcium level with abdominal obesity according to the waist circumference (WC) and the associated factors.

MATERIALS AND METHODS

A cross-sectional study was carried out at private health-care center. A total of 291 patients, aged 18 years and above, with type 2 diabetes mellitus who attended the clinic from May 2017 through March 2018 were included. Sociodemographic, clinical, and laboratory data were obtained from the medical records of patients. Statistical analysis was carried out using the Statistical Package for the Social Sciences software (SPSS, version 23). Abdominal obesity was defined by WC ≥ 80cm in women and ≥94cm in men.

RESULTS

A total number of 291 participants participated in the study. Among these participants, 42.6% ( = 124) were male and 57.4% ( = 167) were female. The average age of respondents was 55.99 ± 9.81 years. Among the male participants, 90 (72.6%) (95% confidence interval [CI]: 64.6%-80.5%) were abdominally obese as were 154 participants (92.2%) (95% CI: 88.1%-96.3%) among females. Overall, 244 participants (83.8%) (95% CI: 79.6%-88.1%) were abdominally obese. The results of statistical modeling showed that gender, smoking status, physical activity, and serum calcium are strong determinants of abdominal obesity.

CONCLUSION

This study revealed a significant association of abdominal obesity and serum calcium level among patients with diabetes.

摘要

引言

本研究旨在根据腰围（WC）及相关因素探寻血清钙水平与腹部肥胖之间的关联。

材料与方法

在一家私立医疗保健中心开展了一项横断面研究。纳入了2017年5月至2018年3月期间到该诊所就诊的291名年龄在18岁及以上的2型糖尿病患者。从患者的病历中获取社会人口统计学、临床和实验室数据。使用社会科学统计软件包（SPSS，版本23）进行统计分析。腹部肥胖的定义为女性腰围≥80厘米，男性腰围≥94厘米。

结果

共有291名参与者参与了该研究。在这些参与者中，42.6%（n = 124）为男性，57.4%（n = 167）为女性。受访者的平均年龄为55.99±9.81岁。在男性参与者中，90人（72.6%）（95%置信区间[CI]：64.6%-80.5%）腹部肥胖，女性参与者中有154人（92.2%）（95%CI：88.1%-96.3%）腹部肥胖。总体而言，244名参与者（83.8%）（95%CI：79.6%-88.1%）腹部肥胖。统计建模结果表明，性别、吸烟状况、身体活动和血清钙是腹部肥胖的重要决定因素。