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脑淀粉样血管病相关性炎症(CAARI):病例报告。

Cerebral amyloid angiopathy-related inflammation (CAARI): case report.

机构信息

Department of Neurology, Pomeranian Medical University in Szczecin, Poland.

Department of Radiology, Pomeranian Medical University in Szczecin, Poland.

出版信息

Folia Neuropathol. 2019;57(2):205-210. doi: 10.5114/fn.2019.86297.

Abstract

Cerebral amyloid angiopathy-related inflammation is a new disease entity whose proper diagnosis may be difficult due to the fact that the early phase and radiological image resemble other conditions such as intracerebral haemorrhage or proliferative disorder. Also, the brain biopsy, which is an important part of the evaluation to confirm the diagnosis and rule out mimics, cannot be performed in each patient. In this paper we present the case of a 58yearold man who was correctly diagnosed with cerebral amyloid angiopathy-related inflammation (CAARI) based on the results of the histopathological examination of the brain tissue, which was possible mainly owing to the inclusion of the expansive process as the underlying cause in the initial differentiation. Further progression of the disease, despite applying treatment of increasing intensity in response to progressive deterioration of the patient's condition, revealed the multiplicity of clinical courses that a new and not easily pinpointed entity can take.

摘要

脑淀粉样血管病相关性炎症是一种新的疾病实体,由于其早期阶段和影像学表现类似于其他疾病,如脑出血或增生性疾病,因此正确诊断可能较为困难。此外,脑活检作为评估的重要组成部分,对于确认诊断和排除类似疾病至关重要,但并非每个患者都能进行。本文报告了一例 58 岁男性患者的病例,该患者的脑淀粉样血管病相关性炎症(CAARI)的诊断主要基于脑组织的组织病理学检查结果,这主要得益于将扩展性病变作为初始鉴别诊断的基础病因。尽管针对患者病情的逐渐恶化,增加了治疗的强度,但疾病仍在继续进展,这揭示了一种新的、不易确定的实体可能具有的多种临床病程。

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