高产毒素但无毒的白喉棒状杆菌帕克-威廉姆斯8型菌株不产生铁载体。
Highly toxinogenic but avirulent Park-Williams 8 strain of Corynebacterium diphtheriae does not produce siderophore.
作者信息
Russell L M, Holmes R K
出版信息
Infect Immun. 1985 Feb;47(2):575-8. doi: 10.1128/iai.47.2.575-578.1985.
Abstract
The highly toxinogenic Park-Williams 8 strain of Corynebacterium diphtheriae grows slowly in vitro and is avirulent. C. diphtheriae Park-Williams 8 is defective in iron uptake and does not produce the corynebacterial siderophore corynebactin. Addition of partially purified corynebactin stimulated iron uptake and growth of iron-deprived C. diphtheriae Park-Williams 8 cells.
摘要
产毒力极强的白喉棒状杆菌帕克-威廉姆斯8型菌株在体外生长缓慢且无毒力。白喉棒状杆菌帕克-威廉姆斯8型在铁摄取方面存在缺陷，不产生棒状杆菌铁载体白喉杆菌素。添加部分纯化的白喉杆菌素可刺激缺铁的白喉棒状杆菌帕克-威廉姆斯8型细胞的铁摄取和生长。
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